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See Latest ArticlesProgestin and thrombin regulate tissue factor expression in human term decidual cells
Journal of Clinical Endocrinology and Metabolism, 03/24/09
Lockwood CF et al. - In human term placental sections, DC-expressed TF exceeds that of other cell types at the maternal-fetal interface and is localized at the cell membranes where it can bind to factor VII and meet the hemostatic demands of labor and delivery via thrombin formation. Unlike the general concept that TF is constitutive in cells that highly express it, MPA and thrombin significantly enhanced TF expression in term DC monolayers.
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