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Specific local cardiovascular changes of N-epsilon-(carboxymethyl)lysine, VEGF, and Smad2 in the developing embryos coincide with maternal diabetes induced Congenital Heart Defects
Diabetes, 02/09/09

Roest PAM et al. - From the results the authors can conclude that maternal diabetes results in transient and localized alterations in CML, VEGF expression and Smad2 phosphorylation overlapping with those regions of the developing heart that are most sensitive to diabetes induced CHD.

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