Endocrinology Medical News about 55CT polymorphism of UCP3 gene - low-carbohydrate diet - low-fat diet

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Modulation of Insulin Concentrations and Metabolic Parameters in Obese Patients by 55CT Polymorphism of the UCP3 Gene Secondary to Two Hypocaloric Diets
Hormone and Metabolic Research, 09/30/08

De Luis DA et al. - Carriers of the T variant experienced decreases in BMI, weight, and fat mass on both diets, without statistical changes in biochemical parameters. In probands with both C alleles, both diets decreased insulin concentrations, blood pressure, and leptin concentrations. Weight reduction was similar with C and T alleles, independent of macronutrient distribution.

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