van Summeren MJH et al. - Vitamin K may be one of multiple risk factors for low bone mass in children with juvenile idiopathic arthritis (JIA), in addition to other recognized determinants of bone mass. Methods
Aim was to study the vitamin K status of bone and its association with bone mass properties in children with JIA
A cross sectional study in 55 children with JIA and 54 healthy controls between 6-18 yrs of age
Bone markers, ultrasound bone mass properties and vitamin K status of bone were determined
Results
Overall, no differences in vitamin K status of bone between the study groups
Among children with JIA, a high ratio of ucOC/cOC indicating low vitamin K status was associated with low bone ultrasound parameters
Children with a high vitamin K status had markedly higher bone properties
This association was independent of physical activity, age, gender and BMI
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