Langsetmo LA et al. – Antiresorptive therapy is associated with a clinically important reduction in low-trauma nonvertebral fracture risk among community-dwelling women aged ≥50, however may be less effective for women ≥75 w/o major risk factors. Methods
Study to determine the association between antiresorptive use and low-trauma nonvertebral fracture in women 50 and older
A retrospective nested case-control study: 5,979 eligible women with 453 cases and 1,304 matched controls
Results
The current use of antiresorptives was associated with a decreased risk of fracture
Major risk factors were prevalent low-trauma fracture, vertebral deformity (grade 2+), and BMD T-score ≤ -2.5
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