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Cerebrospinal Fluid Dehydroepiandrosterone Levels Are Correlated with Brain Dehydroepiandrosterone Levels, Elevated in Alzheimer's Disease, and Related to Neuropathological Disease Stage
Journal of Clinical Endocrinology and Metabolism, 05/14/08

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Free Abstract

Naylor JC et al. - These findings indicate that CSF DHEA and pregnenolone levels are correlated with temporal cortex brain levels of these neurosteroids, and that CSF DHEA is elevated in AD and related to neuropathological disease stage. Neurosteroids may thus be relevant to the pathophysiology of AD.

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