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idiopathic osteoporosis;physical training Article Summary

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Effects of physical training on bone mineral density in fertile women with idiopathic osteoporosis
Clinical Rheumatology, 05/22/08
Print     Email This Article     Save in My Library   Free Abstract
Bergström I et al. - There is no evidence-based therapy for women with idiopathic osteoporosis. It is therefore important to elucidate the impact of moderate physical activity in this group of patients.

Methods
  • A study to investigate whether moderate physical training can improve the bone mineral density (BMD) in women with idiopathic osteoporosis
  • 10 pre-menopausal women (age: 24–44 yrs) diagnosed with idiopathic osteoporosis were enrolled
  • The physical training program: 3 fast 30-min walks plus 1 or 2 sessions of 1-h training/wk during 1 yr
  • All pts were given supplements of vitamin D and calcium
  • BMD was measured in the femoral neck area and the lumbar spine by dual energy X-ray absorptiometry
  • The measurements were performed at baseline and after 12 mos of training
  • They were compared with the measurements at the time of diagnosis, 1–3 yrs before the study

Results
  • Mean BMD in 8 women who fulfilled 12 mo training had BMD at start 0.88 (0.08) g/cm2 in the spine and 0.76 (0.13) g/cm2 in the femoral neck
  • The mean spine BMD increase was 0.031 g/cm2 (3.5%) after 1 yr of training
  • The mean increment in BMD in the femoral neck was 0.007 g/cm2 (0.9%) after the intervention
  • However, the bone loss during the 1- to 3-yr period from diagnosis to study start was, on average, 0.045 g/cm2 or 5.0% in the femoral neck thus indicating a positive indirect effect of the intervention

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