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FDA Update: Thyrotropin Approved For Thyroid Cancer Ablation
Tracy Hampton, PhD, MDLinx Oncology

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Click the title below to leave the MDLinx Network and go to the Journal's Website

Mechanisms of nongenomic actions of thyroid hormone
Frontiers in Neuroendocrinology, 04/17/08

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Free Abstract

Davis PJ et al. - The nongenomic actions of thyroid hormone require a plasma membrane receptor or nuclear receptors located in cytoplasm. The plasma membrane receptor is located on integrin ?V?3 at the Arg-Gly-Asp recognition site important to the binding by the integrin of extracellular matrix proteins. l-Thyroxine (T4) is bound with greater affinity at this site than 3,5,3?-triiodo-l-thyronine (T3).

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