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Article Summary

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A case of hypocortisolemic clinical Cushing's syndrome
Annals of Saudi Medicine, 04/10/08

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Free Abstract

Al-Shoumer KAS et al. - The symptoms and signs of Cushing’s syndrome result directly from chronic exposure to excess glucocorticoids. Most actions of glucocorticoids are mediated by the glucocorticoid recceptor. Several polymorphisms in the gene coding for the glucocorticoid receptor have been described and these may contribute considerably to the observed variaability in glucocorticoid sensitivity.

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