Herrick B - The 2004 report from the Consensus Conference Panel on Subclinical Thyroid Disease (CCPSTD) Independent Expert Panel does not recommend routine treatment for patients with TSH levels between 4.5 and 10 mIU per L, but thyroid function tests should be repeated at six- to 12-month intervals to monitor for changes in TSH levels. For TSH levels above 10 mIU per L, the evidence is too inconclusive to recommend for or against treatment. The CCPSTD recommendations are in parallel with the 2004 recommendations from the U.S. Preventive Services Task Force, which state that the benefit of treatment is inconsistent and the potential adverse effects of over-treatment may affect a substantial number of persons. Evidence is inconsistent for dyslipidemia, atherosclerosis, and a decreased quality of life in adults with subclinical hypothyroidism in the general population.
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