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See Latest ArticlesA German family with glucocorticoid-remediable aldosteronism
Nephrology Dialysis Transplantation, 03/27/07
Oliver Vonend, et al. - The prevalence of primary hyperaldosteronism (PHA) in the hypertensive population has increased in recent years. Glucocorticoid-remediable aldosteronism (GRA) is a rare monogenic form of PHA...Conclusions: The aldosterone/renin ratio is a valid screening and sodium loading a valid confirmation test in GRA. Determination of elevated urinary excretion of specific aldosterone metabolites and identification of the chimeric gene are mandatory since a lacking blood pressure response to dexamethasone can be misleading
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