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Rush, Jordan MD, et al. - Hypothyroidism is a common endocrine disease, which, in addition to its classic signs and symptoms, can present with primary complaints of myopathy. Myopathy can cause skeletal muscle weakness, tenderness, and pain and is often associated with elevated creatine kinase levels. There are many neuromuscular causes of myopathy, including inflammatory and infectious myopathies, metabolic and hereditary myopathies, and those caused by drugs or toxins

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