Management of the child with congenital adrenal hyperplasia
Hindmarsh PC et al. - The starting dose should be 150 mug/m2/day, and the dose thereafter titrated to plasma renin activity and blood pressure. Despite adequate glucocorticoid substitution and concordance with medical therapy, control can be difficult during puberty due to alterations in the clearance of hydrocortisone, and dosing schedules may need to be adjusted to account for this. [more...]
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