Reducing the cost of detection of congenital heart disease in fetuses of women with pregestational diabetes mellitus Bernard LS et al. - Detection of major CHD was excellent with both comprehensive prenatal ultrasound and echocardiography. Echocardiography added little to the prenatal diagnosis of CHD if the comprehensive ultrasound examination was normal. The highest cost-benefit ratio and most efficacious protocol for screening based on the data would be comprehensive ultrasound with prenatal and postnatal echocardiography only as indicated. [more...]