Impaired Fat-induced Thermogenesis in Obese Subject
Ellen E, et al. – Does energy expenditure change before and 3 hours after a high-fat load in obese people?
>Summary: A Study on 701 obese subjects and a lean reference group consist of 113 individuals from seven European countries. The study was for one day and outcome measures were fasting and 3-hour postprandial energy expenditures, metabolites and hormones
Outcomes: The study showed that insulin resistance, fasting plasma free fatty acids, and cortisol were positively associated, whereas fasting plasma leptin and insulin-like growth factor-1 were negatively associated, with resting energy expenditure. Therefore we can conclude that the 3-hour fat-induced thermogenic response is reduced in obesity. It is unclear that this response contributes to obesity or it is the result of it [more...]
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