Depressive tendency in children with growth hormone deficiency
Journal of Paediatrics and Child Health, 10/23/2009
|
Abe S et al. – A depressive tendency was relatively common in children with growth hormone deficiency, and the Depression Self–Rating Scale for Children was decreased after growth hormone treatment. These results suggest that growth hormone treatment may ... positive effects on the psychosocial aspects in children with growth hormone deficiency.
[more...]
|
Placental growth hormone and growth hormone binding protein are first trimester maternal serum markers of Down syndrome
Prenatal Diagnosis, 10/22/2009
|
Christiansen M et al. – Placental growth hormone (PGH) is synthesised by the placenta, and its function is modulated by growth hormone binding protein (GHBP). The potential
[more...]
|
Comparison of glucose and lipid metabolism and bone mineralization in patients with growth hormone deficiency with and without long-term growth hormone replacement
Metabolism-Clinical and Experimental, 10/26/2009
|
Roemmler J et al. – Long–term GH substitution trends to beneficially influence fasting glucose and glucose tolerance, although differences are sparse. Growth hormone substitution alone does ... significantly impact on insulin sensitivity, lipid metabolism, and BMD in patients with pituitary insufficiency.
[more...]
|
Endocrine Regulation of Feto-Placental Growth
Hormone Research, 10/27/2009
|
Fowden AL et al. – Hormones are both growth stimulatory and growth inhibitory in utero. They regulate tissue growth and development by controlling the rates of cell proliferation, apoptosis and differentiation in many fetal tissues. This review examines the role of hormones in feto ... ndash;placental growth with particular emphasis on insulin, the insulin–like growth factors and glucocorticoids.
[more...]
|
Growth hormone and protein metabolism
Clinical Nutrition, 11/17/2009
|
Moller N et al. – Growth hormone (GH) and intracellular STAT 5 signalling represents a very old regulatory system and, whereas insulin dominates periprandially, GH may be viewed as the primary anabolic hormone during stress and fasting. GH exerts ... metabolic effects both directly and through stimulation of IGF–I, insulin, and free fatty acids (FFA).
[more...]
|
The value of the oral glucose tolerance test, random serum growth hormone and mean growth hormone levels in assessing the postoperative outcome of patients with acromegaly
Clinical Endocrinology, 11/16/2009
|
Karavitaki N et al. – The hormonal data obtained from an OGTT (mean and nadir GH) can provide comprehensive information ... a morning fasting GH sample has an excellent positive predictive value in predicting biochemical cure and an optimal prognostic profile in predicting “safe” mean GH levels.
[more...]
|
Growth hormone and bone
Current Opinion in Endocrinology, Diabetes and Obesity, 11/03/2009
|
Tritos NA et al. – GH may have a relevant role in bone physiology and several disease states in addition to growth hormone deficiency. Although the salutary effects of GH replacement on bone growth and bone density are well characterized, additional studies are ... required to examine the impact of GH replacement on fracture risk as well as potential benefits in osteoporosis.
[more...]
|
Relationship of peak growth hormone to cardiovascular parameters, waist circumference, lipids and glucose in HIV-infected patients and healthy adults
Clinical Endocrinology, 11/17/2009
|
Lo J et al. – Relative growth hormone (GH) deficiency is highly prevalent in patients with HIV. The purpose of this study was to investigate ... anthropometric parameters in HIV patients and non–HIV controls. Reduced GH secretion is independently associated with dyslipidaemia and higher glucose, among HIV patients with abdominal fat accumulation.
[more...]
|
Reassessment of the Growth Hormone Status in Young Adults with Childhood-Onset Growth Hormone Deficiency: Reappraisal of Insulin Tolerance Testing
Journal of Clinical Endocrinology and Metabolism, 10/29/2009
|
Secco A et al. – The adopted peak GH to ITT below 5.62 microg/liter is an accurate diagnostic cutoff point for HLGHD in young adults with COGHD ... ndash;I is a reliable marker providing information about the severity of GHD. Careful follow–up is required for subjects with discordant ITT and IGF–I results.
[more...]
|
Hypopituitarism due to sports related head trauma and the effects of growth hormone replacement in retired amateur boxers
Pituitary, 10/29/2009
|
Tanriverdi F et al. – Traumatic brain injury (TBI) has been recently recognized as a leading cause of pituitary dysfunction. Current data clearly demonstrated that sports ... results in pituitary hormone deficiencies, isolated growth hormone (GH) deficiency in particular. GHRT may have beneficial effects in retired boxers with severe isolated GH deficiency due to sports related head trauma. But more data with higher number of boxers and longer GHRT duration are warranted
[more...]
|
