Low vitamin D levels increase risk of GDM
As reported in Acta Diabetologica, the OR for developing gestational diabetes mellitus was 1.48 for each 1 SD decrease in the 25OHD level. A decrease in 25OHD was also shown to be associated with increased insulin resistance in the second trimester.
Parenteral vitamin D improves insulin sensitivity
As reported in Swiss Medical Weekly, supplemental vitamin D3 (300,000 IU im) in patients (n=55) with T2DM of > 10 y duration resulted in a 12.8% decrease in HOMA-IR at 6 months compared to an increase of 10% in patients who received placebo.
Hypoglycemia in hospitalized diabetics and increased mortality
As reported in Endocrine Practice, hospitalized diabetics with secondary hypoglycemia (n=46408) are at increased risk for mortality (OR=1.24), early readmission (OR=1.20), and increased length of stay (OR=1.24) compared to hospitalized diabetics without hypoglycemic episodes.