Endocrinology - Metabolism and Growth News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (6) Full Text Articles (192) Focus on Pediatrics

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

981 Colonic neoplasia in acromegaly: increased proliferation or deceased apoptosis Pituitary, April 12, 2011

982 Associations of Self-Reported Periodontal Disease With Metabolic Syndrome and Number of Self-Reported Chronic Conditions Full Text Preventing Chronic Disease, April 12, 2011

983 P Wave Indices, Obesity, and the Metabolic Syndrome: The Atherosclerosis Risk in Communities Study Obesity, April 8, 2011

984 Increasing Leisure Time Physical Activity is Associated With Less Prevalence of the Metabolic Syndrome in Healthy Middle-Aged Men Angiology, April 8, 2011

985 Relation of G1359A polymorphism of the cannabinoid receptor gene (CB1) with metabolic syndrome by ATP III clasification Diabetes/Metabolism Research and Reviews, April 8, 2011

986 Low Incidence of Adrenal Insufficiency after Transsphenoidal Surgery in Patients with Acromegaly: A Long-Term Follow-Up Study Full Text Journal of Clinical Endocrinology and Metabolism, April 7, 2011

987 Clinical and metabolic characteristics of acromegalic patients with high IGF-I/normal GH levels during somatostatin analog treatment European Journal of Endocrinology, April 7, 2011

988 Diurnal secretion profiles of growth hormone, thyrotropin and prolactin in Parkinsons disease Journal of Neuroendocrinology, April 6, 2011

989 Association of metabolic syndrome and diabetes with subclinical coronary stenosis and plaque subtypes in middle-aged individuals Diabetic Medicine, April 4, 2011

990 Vascular biology of metabolic syndrome Journal of Vascular Surgery, April 1, 2011

991 Serum Antioxidant Status Is Associated with Metabolic Syndrome among U.S. Adults in Recent National Surveys The Journal of Nutrition, March 31, 2011

992 Final Adult Height in Children with Congenital Adrenal Hyperplasia Treated with Growth Hormone Full Text Journal of Clinical Endocrinology and Metabolism, March 31, 2011

993 Vegetarian Dietary Patterns Are Associated With a Lower Risk of Metabolic Syndrome: The Adventist Health Study 2 Full Text Diabetes Care, March 31, 2011

994 Growth hormone treatment for Turner syndrome in Australia reveals that younger age and increased dose interact to improve response Clinical Endocrinology, March 31, 2011

995 Cross-Sectional Evidence of a Signaling Pathway from Bone Homeostasis to Glucose Metabolism Full Text Journal of Clinical Endocrinology and Metabolism, March 30, 2011

996 Higher consumption of sugar-sweetened beverages is associated with increased risk of developing type 2 diabetes or metabolic syndrome Evidence Based Nursing, March 29, 2011

997 Growth Hormone Treatment in Short Children Born Prematurely—Data from KIGS Full Text Journal of Clinical Endocrinology and Metabolism, March 29, 2011
Exclusive Author Commentary

998 Bone geometry and volumetric bone mineral density in girls with Turner syndrome of different pubertal stages Clinical Endocrinology, March 28, 2011

999 Health-related quality of life in metabolic syndrome: The Korea National Health and Nutrition Examination Survey 2005 Diabetes Research and Clinical Practice, March 28, 2011

1000 Visceral Adipocyte Hypertrophy is Associated With Dyslipidemia Independent of Body Composition and Fat Distribution in Women Full Text Diabetes, March 28, 2011

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Ketoacidosis as the initial clinical condition in nine patients with acromegaly: A review of 860 cases at a single institute European Journal of Endocrinology, May 9, 2013 Review Article

2 Developing long-acting growth hormone formulations Clinical Endocrinology, May 13, 2013 Review Article

3 Growth hormone therapy with norditropin (somatropin ) in growth hormone deficiency Expert Opinion on Biological Therapy, May 29, 2013 Review Article

4 Effects of Medical Therapies for Acromegaly on Glucose Metabolism European Journal of Endocrinology, May 13, 2013

5 Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies Current Opinion in Lipidology, May 24, 2013 Review Article

6 GH treatment to final height produces similar height gains in patients with SHOX deficiency and Turner syndrome: results of a multicenter trial Journal of Clinical Endocrinology and Metabolism, May 30, 2013

7 Beyond the Sympathetic Tone: The New Brown Fat Activators Cell Metabolism, May 8, 2013 Review Article

8 Circulating levels of pegvisomant and endogenous GH during prolonged pegvisomant therapy in patients with acromegaly Clinical Endocrinology, May 14, 2013 Review Article

9 Effects of Ingestion Routes on Hormonal and Metabolic Profiles in Gastric-Bypassed Humans Journal of Clinical Endocrinology and Metabolism, May 10, 2013 Review Article

10 Serum Insulin-Like Growth Factor-I, Metabolic Syndrome and Incident Cardiovascular Disease in Older people: A Population-Based Study European Journal of Endocrinology, January 7, 2013 Review Article

11 Challenging the Fructose Hypothesis: New Perspectives on Fructose Consumption and Metabolism Advances in Nutrition: An International Review Journal, April 3, 2013 Review Article

12 Metabolically healthy obesity and risk of mortality: Does the definition of metabolic health matter? Diabetes Care, May 3, 2013

13 Glucocorticoid-Induced Hyperglycemia The American Journal of the Medical Sciences, April 11, 2013 Review Article

14 Prevalence of cerebral aneurysm in patients with acromegaly Pituitary, May 21, 2013 Review Article

15 Thyroid hormones and the metabolic syndrome European Thyroid Journal, May 28, 2013 Review Article

16 Parathyroid and calcium metabolism disorders during pregnancy Gynecological Endocrinology, May 28, 2013

17 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

18 Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Evidence Based Medicine Clinical Guideline

19 Todays adult generations are less healthy than their predecessors: generation shifts in metabolic risk factors: the Doetinchem Cohort Study European Journal of Preventive Cardiology, May 2, 2013

20 The place of medical treatment of acromegaly: current status and perspectives Expert Opinion on Pharmacotherapy, May 23, 2013 Review Article

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Metabolism and Growth News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology