Endocrinology - Metabolism and Growth News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (4) Full Text Articles (192) Focus on Parathyroid/Adrenal

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

81 Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting Cell Metabolism, May 7, 2013 Review Article

82 Two weeks of reduced activity decreases leg lean mass and induces anabolic resistance of myofibrillar protein synthesis in healthy elderly Journal of Clinical Endocrinology and Metabolism, May 6, 2013 Review Article

83 Metabolically healthy obesity and risk of mortality: Does the definition of metabolic health matter? Diabetes Care, May 3, 2013 Clinical Article

84 Complex Rhythmicity and Age Dependence of Growth Hormone Secretion Are Preserved in Patients With Acromegaly: Further Evidence for a Present Hypothalamic Control of Pituitary Somatotropinomas Journal of Clinical Endocrinology and Metabolism, May 3, 2013 Review Article

85 Serum osteocalcin levels in relation to metabolic syndrome in Chinese postmenopausal women Menopause, May 3, 2013 Clinical Article

86 Greater impairment of postprandial triacylglycerol than glucose response in metabolic syndrome subjects with fasting hyperglycaemia Metabolism, May 3, 2013 Review Article

87 Todays adult generations are less healthy than their predecessors: generation shifts in metabolic risk factors: the Doetinchem Cohort Study European Journal of Preventive Cardiology, May 2, 2013 Clinical Article

88 The preventive effect of uncarboxylated osteocalcin against free fatty acid-induced endothelial apoptosis through the activation of phosphatidylinositol 3-kinase/Akt signaling pathway: Uncarboxylated osteocalcin and endothelial apoptosis Metabolism, May 2, 2013 Review Article

89 Patients With Celiac Disease Have a Lower Prevalence of Non-Insulin-Dependent Diabetes Mellitus and Metabolic Syndrome Gastroenterology, April 30, 2013 Review Article

90 Development and a Pilot Test of an Internet-Based Cardiovascular Risk Reduction Program for Korean Male Workers With Metabolic Syndrome Computers Informatics Nursing, April 30, 2013 Review Article

91 Insulin Resistance of Protein Metabolism in Type 2 Diabetes and Impact on Dietary Needs: A Review Canadian Journal of Diabetes, April 29, 2013 Review Article

92 Inadequate Sleep as a Contributor to Obesity and Type 2 Diabetes Canadian Journal of Diabetes, April 29, 2013 Clinical Article

93 Comparison of the abilities of the plasma triglyceride/high-density lipoprotein cholesterol ratio and the metabolic syndrome to identify insulin resistance Diabetes & Vascular Disease Research, April 29, 2013 Review Article

94 Effects of Recombinant Human Growth Hormone for 1 Year on Body Composition and Muscle Strength in Children on Long-Term Steroid Therapy: Randomized Controlled, Delayed-Start Study Journal of Clinical Endocrinology and Metabolism, April 29, 2013 Clinical Article

95 Obesity-related dysregulation of the tryptophan-kynurenine metabolism: Role of age and parameters of the metabolic syndrome Obesity, April 29, 2013 Review Article

96 Chemopreventive effects of metformin on obesity-associated endometrial proliferation American Journal of Obstetrics and Gynecology, April 26, 2013 Clinical Article

97 Different Long-Term Response to Growth Hormone Therapy in Small- versus Appropriate-for-Gestational-Age Children with Growth Hormone Deficiency Hormone Research in Paediatrics, April 26, 2013 Review Article

98 High-sensitivity C-reactive protein and white blood cell count equally predict development of the metabolic syndrome in a Japanese health screening population Acta Diabetologia, April 26, 2013 Review Article
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99 Nonalcoholic fatty liver and metabolic syndrome in Italy: results from a multicentric study of the Italian Arteriosclerosis society Acta Diabetologia, April 26, 2013 Review Article

100 Study of Primary IGF-1 Deficiency in Egyptian Children with Idiopathic Short Stature Hormone Research in Paediatrics, April 26, 2013 Clinical Article

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Ketoacidosis as the initial clinical condition in nine patients with acromegaly: A review of 860 cases at a single institute European Journal of Endocrinology, May 9, 2013 Review Article

2 Developing long-acting growth hormone formulations Clinical Endocrinology, May 13, 2013 Review Article

3 Growth hormone therapy with norditropin (somatropin ) in growth hormone deficiency Expert Opinion on Biological Therapy, May 29, 2013 Review Article

4 Effects of Medical Therapies for Acromegaly on Glucose Metabolism European Journal of Endocrinology, May 13, 2013

5 Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies Current Opinion in Lipidology, May 24, 2013 Review Article

6 GH treatment to final height produces similar height gains in patients with SHOX deficiency and Turner syndrome: results of a multicenter trial Journal of Clinical Endocrinology and Metabolism, May 30, 2013

7 Beyond the Sympathetic Tone: The New Brown Fat Activators Cell Metabolism, May 8, 2013 Review Article

8 Circulating levels of pegvisomant and endogenous GH during prolonged pegvisomant therapy in patients with acromegaly Clinical Endocrinology, May 14, 2013 Review Article

9 Effects of Ingestion Routes on Hormonal and Metabolic Profiles in Gastric-Bypassed Humans Journal of Clinical Endocrinology and Metabolism, May 10, 2013 Review Article

10 Serum Insulin-Like Growth Factor-I, Metabolic Syndrome and Incident Cardiovascular Disease in Older people: A Population-Based Study European Journal of Endocrinology, January 7, 2013 Review Article

11 Challenging the Fructose Hypothesis: New Perspectives on Fructose Consumption and Metabolism Advances in Nutrition: An International Review Journal, April 3, 2013 Review Article

12 Metabolically healthy obesity and risk of mortality: Does the definition of metabolic health matter? Diabetes Care, May 3, 2013

13 Glucocorticoid-Induced Hyperglycemia The American Journal of the Medical Sciences, April 11, 2013 Review Article

14 Prevalence of cerebral aneurysm in patients with acromegaly Pituitary, May 21, 2013 Review Article

15 Thyroid hormones and the metabolic syndrome European Thyroid Journal, May 28, 2013 Review Article

16 Parathyroid and calcium metabolism disorders during pregnancy Gynecological Endocrinology, May 28, 2013

17 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

18 Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Evidence Based Medicine Clinical Guideline

19 Todays adult generations are less healthy than their predecessors: generation shifts in metabolic risk factors: the Doetinchem Cohort Study European Journal of Preventive Cardiology, May 2, 2013

20 The place of medical treatment of acromegaly: current status and perspectives Expert Opinion on Pharmacotherapy, May 23, 2013 Review Article

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Metabolism and Growth News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology