Endocrinology - Metabolism and Growth News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (4) Full Text Articles (192) Focus on Diabetes

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

501 Alterations in Gastrointestinal, Endocrine, and Metabolic Processes After Bariatric Roux-en-Y Gastric Bypass Surgery Diabetes Care, August 27, 2012

502 Severe growth hormone deficiency is rare in surgically-cured acromegalics Pituitary, August 27, 2012

503 Regulation of Physiological and Metabolic Function of Muscle by Female Sex Steroids Medicine and Science in Sports and Exercise, August 24, 2012

504 Associations of the lower urinary tract symptoms with the lifestyle, prostate volume, and metabolic syndrome in the elderly males The Aging Male, August 24, 2012

505 Metabolic syndrome and vascular risk estimation in a Mediterranean non-diabetic population without cardiovascular disease European Journal of Internal Medicine , August 23, 2012

506 Obstructive sleep apnea hypopnea syndrome and metabolic syndrome: A synergistic cardiovascular risk factor Journal of the American Academy of Nurse Practitioners, August 23, 2012

507 Metabolic syndrome meets osteoarthritis Nature Reviews Rheumatology , August 22, 2012

508 Blood cadmium, mercury, and lead and metabolic syndrome in South Korea: 2005–2010 Korean National Health and Nutrition Examination Survey American Journal of Industrial Medicine, August 22, 2012

509 Sedentary behaviour and clustered metabolic risk in adolescents: The HELENA study Nutrition, Metabolism & Cardiovascular Diseases, August 21, 2012

510 Obesity, Metabolic Syndrome and the Risk of Development of Colonic Diverticulosis Digestion, August 21, 2012

511 Heterogeneity in sex differences in the metabolic syndrome in Dutch white, Surinamese African and South Asian populations Diabetic Medicine, August 21, 2012

512 Effects of growth hormone deficiency on body composition and biomarkers of cardiovascular risk after definitive therapy for acromegaly Clinical Endocrinology, August 20, 2012

513 Prediction of metabolic syndrome among postmenopausal Ghanaian women using obesity and atherogenic markers Full Text Lipids in Health and Disease, August 20, 2012

514 Insulin Sensitivity Modulates the Growth Response during the First Year of High-Dose Growth Hormone Treatment in Short Prepubertal Children Born Small for Gestational Age Hormone Research in Paediatrics, August 17, 2012

515 Change in Total Body Water as a Predictive Tool for Growth Hormone Treatment Response Hormone Research in Paediatrics, August 17, 2012

516 The Value of the Metabolic Syndrome Concept in Elderly Adults: Is It Worth Less Than the Sum of Its Parts? Journal of the American Geriatrics Society, August 17, 2012

517 Accurate Long-Term Prediction of Height during the First Four Years of Growth Hormone Treatment in Prepubertal Children with Growth Hormone Deficiency or Turner Syndrome Hormone Research in Paediatrics, August 17, 2012

518 Does the metabolic syndrome predict subclinical atherosclerotic damage in an asymptomatic population at intermediate cardiovascular risk Nutrition, Metabolism & Cardiovascular Diseases, August 17, 2012

519 Identification of a Novel Heterozygous IGF1 Splicing Mutation in a Large Kindred with Familial Short Stature Hormone Research in Paediatrics, August 17, 2012

520 The Ubiquitous Mineralocorticoid Receptor: Clinical Implications Current Hypertension Reports, August 17, 2012

50 available pages First Previous 26 27 28 29 30 31 32 33 34 35 Next Last

Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Challenging the Fructose Hypothesis: New Perspectives on Fructose Consumption and Metabolism Advances in Nutrition: An International Review Journal, April 3, 2013 Review Article

2 Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Evidence Based Medicine Clinical Guideline

3 Telmisartan as a metabolic sartan: The first meta-analysis of randomized controlled trials in metabolic syndrome Journal of the American Society of Hypertension, April 24, 2013

4 Glucocorticoid-Induced Hyperglycemia The American Journal of the Medical Sciences, April 11, 2013 Review Article

5 Characterizing Short Stature by Insulin-like Growth Factor Axis Status and Genetic Associations: Results From the Prospective, Cross-sectional, Epidemiogenetic EPIGROW Study Journal of Clinical Endocrinology and Metabolism, April 18, 2013

6 Long-term effects of recombinant human Growth Hormone (rhGH) replacement in adults with Growth Hormone Deficiency (GHD): a systematic review European Journal of Endocrinology, April 11, 2013 Evidence Based Medicine Review Article

7 High-sensitivity C-reactive protein and white blood cell count equally predict development of the metabolic syndrome in a Japanese health screening population Acta Diabetologia, April 26, 2013 Review Article
Exclusive Author Commentary

8 The diagnostic criteria for gestational diabetes: to change or not to change? American Journal of Obstetrics and Gynecology, April 15, 2013

9 Adult growth hormone deficiency – benefits, side effects, and risks of growth hormone replacement Frontiers in Endocrinology, April 24, 2013 Review Article

10 Short-term outcome of patients with preeclampsia Vascular Health and Risk Management, April 25, 2013 Free full text

11 Guidelines Updates in the Treatment of Obesity or Metabolic Syndrome and Hypertension Current Hypertension Reports, April 2, 2013 Clinical Guideline

12 The role of human growth hormone's C-terminal disulfide bridge Growth Hormone & IGF Research, April 19, 2013 Review Article

13 Significance of estimating the glomerular filtration rate for the management of hypertension in type 2 diabetes with microalbuminuria Hypertension Research, April 8, 2013

14 Migraine, headache and development of metabolic syndrome: An 11 year follow-up in the HUNT Study Pain, April 15, 2013

15 Intake of Whole-Grain and Fiber-Rich Rye Bread Versus Refined Wheat Bread Does Not Differentiate Intestinal Microbiota Composition in Finnish Adults with Metabolic Syndrome The Journal of Nutrition, April 1, 2013

16 Status of Cardiovascular Health in US Adolescents Circulation, April 10, 2013

17 Hepatic manifestations of metabolic syndrome Diabetes/Metabolism Research and Reviews, March 14, 2013 Review Article

18 Insulin Resistance of Protein Metabolism in Type 2 Diabetes and Impact on Dietary Needs: A Review Canadian Journal of Diabetes, April 29, 2013 Review Article

19 Study of Primary IGF-1 Deficiency in Egyptian Children with Idiopathic Short Stature Hormone Research in Paediatrics, April 26, 2013

20 Sleep Disordered Breathing as a Risk of Cardiac Events in Subjects With Diabetes Mellitus and Normal Exercise Echocardiographic Findings The American Journal of Cardiology, April 4, 2013

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Metabolism and Growth News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology