Endocrinology - Metabolism and Growth News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (6) Full Text Articles (192) Focus on Pediatrics

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

21 Influence of heart rate at rest for predicting the metabolic syndrome in older Chinese adults Acta Diabetologia, June 10, 2013 Review Article

22 Familial acromegaly due to aryl hydrocarbon receptor-interacting protein (AIP) gene mutation in a Turkish cohort Pituitary, June 10, 2013 Clinical Article

23 Insulin-like Growth Factor I and its binding protein 3 in sepsis Growth Hormone & IGF Research, June 6, 2013 Review Article

24 The effect of a period of intensive exercise on the isoform test to detect growth hormone doping in sports Growth Hormone & IGF Research, June 6, 2013 Review Article

25 Insulin Resistance and the Metabolic Syndrome Are Associated With Arterial Stiffness in Patients With Chronic Kidney Disease American Journal of Hypertension, June 6, 2013 Clinical Article

26 Acromegalic patients lost to follow-up: a pilot study Pituitary, June 6, 2013 Review Article

27 Novel compound heterozygous mutations of the growth hormone-releasing hormone receptor gene in a case of isolated growth hormone deficiency Growth Hormone & IGF Research, June 6, 2013

28 Subclinical hypothyroidism and indices for metabolic syndrome in Japanese women: One year follow-up study Journal of Clinical Endocrinology and Metabolism, June 5, 2013 Clinical Article

29 Endoscopic versus microsurgical transsphenoidal surgery for acromegaly: outcomes in a concurrent series of patients using modern criteria for remission Journal of Clinical Endocrinology and Metabolism, June 5, 2013 Review Article

30 Metabolic syndrome profiles, obesity measures and intake of dietary fatty acids in adults: Tehran Lipid and Glucose Study Journal of Human Nutrition and Dietetics, June 5, 2013 Clinical Article

31 Does physical activity during pregnancy adversely influence markers of the metabolic syndrome in adult offspring? A prospective study over two decades Journal of Epidemiology and Community Health, June 5, 2013 Clinical Article

32 The role of the complement system in metabolic organs and metabolic diseases Seminars in Immunology, June 4, 2013 Review Article

33 Metabolic syndrome, C-reactive protein and microalbuminuria in a rural Chinese population: a cross-sectional study Full Text BMC Nephrology, June 4, 2013 Clinical Article

34 Surgical interventions for obesity and metabolic disease Best Practice & Research Clinical Endocrinology & Metabolism, June 4, 2013 Review Article

35 Adipose tissue dysfunction contributes to obesity related metabolic diseases Best Practice & Research Clinical Endocrinology & Metabolism, June 4, 2013 Review Article

36 Leaner and less fit children have a better cardiometabolic profile than their heavier and more fit peers: The Healthy Growth Study Nutrition, Metabolism & Cardiovascular Diseases, May 31, 2013 Clinical Article

37 Areca nut chewing and metabolic syndrome: evidence of a harmful relationship Full Text Nutrition Journal, May 31, 2013 Clinical Article

38 Insulin-like growth factor-I correlates more closely than growth hormone with insulin resistance and glucose intolerance in patients with acromegaly Pituitary, May 31, 2013 Review Article

39 Metabolic syndrome as a predictor of type 2 diabetes, and its clinical interpretations and usefulness Journal of Diabetes Investigation, May 30, 2013 Review Article

40 Changes in both global diet quality and physical activity level synergistically reduce visceral adiposity in men with features of metabolic syndrome The Journal of Nutrition, May 30, 2013 Review Article

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Ketoacidosis as the initial clinical condition in nine patients with acromegaly: A review of 860 cases at a single institute European Journal of Endocrinology, May 9, 2013 Review Article

2 Developing long-acting growth hormone formulations Clinical Endocrinology, May 13, 2013 Review Article

3 Growth hormone therapy with norditropin (somatropin ) in growth hormone deficiency Expert Opinion on Biological Therapy, May 29, 2013 Review Article

4 Effects of Medical Therapies for Acromegaly on Glucose Metabolism European Journal of Endocrinology, May 13, 2013

5 Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies Current Opinion in Lipidology, May 24, 2013 Review Article

6 GH treatment to final height produces similar height gains in patients with SHOX deficiency and Turner syndrome: results of a multicenter trial Journal of Clinical Endocrinology and Metabolism, May 30, 2013

7 Beyond the Sympathetic Tone: The New Brown Fat Activators Cell Metabolism, May 8, 2013 Review Article

8 Circulating levels of pegvisomant and endogenous GH during prolonged pegvisomant therapy in patients with acromegaly Clinical Endocrinology, May 14, 2013 Review Article

9 Effects of Ingestion Routes on Hormonal and Metabolic Profiles in Gastric-Bypassed Humans Journal of Clinical Endocrinology and Metabolism, May 10, 2013 Review Article

10 Serum Insulin-Like Growth Factor-I, Metabolic Syndrome and Incident Cardiovascular Disease in Older people: A Population-Based Study European Journal of Endocrinology, January 7, 2013 Review Article

11 Challenging the Fructose Hypothesis: New Perspectives on Fructose Consumption and Metabolism Advances in Nutrition: An International Review Journal, April 3, 2013 Review Article

12 Metabolically healthy obesity and risk of mortality: Does the definition of metabolic health matter? Diabetes Care, May 3, 2013

13 Glucocorticoid-Induced Hyperglycemia The American Journal of the Medical Sciences, April 11, 2013 Review Article

14 Prevalence of cerebral aneurysm in patients with acromegaly Pituitary, May 21, 2013 Review Article

15 Thyroid hormones and the metabolic syndrome European Thyroid Journal, May 28, 2013 Review Article

16 Parathyroid and calcium metabolism disorders during pregnancy Gynecological Endocrinology, May 28, 2013

17 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

18 Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Evidence Based Medicine Clinical Guideline

19 Todays adult generations are less healthy than their predecessors: generation shifts in metabolic risk factors: the Doetinchem Cohort Study European Journal of Preventive Cardiology, May 2, 2013

20 The place of medical treatment of acromegaly: current status and perspectives Expert Opinion on Pharmacotherapy, May 23, 2013 Review Article

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Metabolism and Growth News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology