Endocrinology - Diagnostics News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

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1 Magnetic resonance imaging (MRI) in paediatric psychoneuroendocrinology: a new frontier for understanding the impact of hormones on emotion and cognition Journal of Neuroendocrinology, May 17, 2013 Review Article

Prior Articles

2 Trabecular homogeneity index derived from plain radiograph to evaluate bone quality Journal of Bone and Mineral Research, May 16, 2013 Review Article

3 Changes in Body Fat Distribution and Fitness Are Associated With Changes in Hemoglobin A_1c After 9 Months of Exercise Training: Results From the HART-D Study Diabetes Care, May 15, 2013 Clinical Article

4 Use of Color Doppler Ultrasonography to Measure Thyroid Blood Flow and Differentiate Graves' Disease from Painless Thyroiditis European Thyroid Journal, May 15, 2013 Review Article

5 Reliability of field methods for estimating body fat Clinical Physiology and Functional Imaging, May 15, 2013 Clinical Article

6 Urinary C-peptide creatinine ratio detects absolute insulin deficiency in Type 2 diabetes Diabetic Medicine, May 14, 2013 Review Article

7 Transportability of the updated diabetes prediction model from Atherosclerosis Risk in Communities Study to a Middle Eastern adult population: community-based cohort study Acta Diabetologia, May 14, 2013

8 Characteristics Associated With Maintenance of Mean A1C <6.5% in People With Dysglycemia in the ORIGIN Trial Diabetes Care, May 10, 2013 Clinical Article

9 Hemoglobin A1c in Pregestational Diabetic Gravidas and the Risk of Congenital Heart Disease in the Fetus Pediatric Cardiology, May 9, 2013 Review Article

10 X-ray verified fractures are associated with finite element analysis derived bone strength and trabecular microstructure in young adult men Journal of Bone and Mineral Research, May 9, 2013 Review Article

11 Cytomorphological Factors and BRAF Mutation Predicting Risk of Lymph Node Metastasis in Preoperative Liquid-Based Fine Needle Aspirations of Papillary Thyroid Carcinoma Acta Cytologica, May 7, 2013 Clinical Article

12 Thyroglobulin levels and thyroglobulin doubling time independently predict a positive 18F-FDG PET/CT scan in patients with biochemical recurrence of differentiated thyroid carcinoma European Journal of Nuclear Medicine & Molecular Imaging, May 6, 2013 Clinical Article

13 Planar Scintigraphy with 123I/99mTc-Sestamibi, 99mTc-Sestamibi SPECT/CT, 11C-Methionine PET/CT, or Selective Venous Sampling Before Reoperation of Primary Hyperparathyroidism The Journal of Nuclear Medicine, May 6, 2013 Clinical Article

14 Could 18F-FDG-PET/CT avoid unnecessary thyroidectomies in patients with cytological diagnosis of follicular neoplasm Langenbeck's Archives of Surgery, May 3, 2013 Clinical Article

15 Efficacy of thyroid ultrasound elastography in differential diagnosis of small thyroid nodules European Journal of Radiology, May 2, 2013 Review Article

16 The value of intraoperative PTH measurements in patients with mild primary hyperparathyroidism Langenbeck's Archives of Surgery, May 2, 2013 Clinical Article

17 Glycemic Control Associated With Secure Patient-Provider Messaging Within a Shared Electronic Medical Record: A Longitudinal Analysis Diabetes Care, May 1, 2013 Clinical Article

18 Mid-term prognostic value of coronary artery disease in patients undergoing transcatheter aortic valve implantation: A meta-analysis of adjusted observational results International Journal of Cardiology, May 1, 2013 Evidence Based Medicine Clinical Article

19 Structured self-monitoring of blood glucose reduces glycated hemoglobin in insulin-treated diabetes Journal of Diabetes Investigation, April 30, 2013 Clinical Article

20 Contrast-induced acute kidney injury and clinical outcomes after intra-arterial and intravenous contrast administration: Risk comparison adjusted for patient characteristics by design American Heart Journal, April 30, 2013 Clinical Article

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Meaning of upper limit of normal range of post-load 1-h plasma glucose level defined by oral glucose tolerance test in Japanese subjects Journal of Diabetes Investigation, April 3, 2013 Review Article

2 Lateral Sacral Imaging in the Morbidly Obese Journal of Orthopaedic Trauma, April 24, 2013

3 Effect of sulfonylurea dose escalation on hemoglobin A1c in Veterans Affairs patients with type 2 diabetes Acta Diabetologia, April 26, 2013 Review Article

4 Effects of metformin on serum insulin and anti-mullerian hormone levels and on hyperandrogenism in patients with polycystic ovary syndrome Gynecological Endocrinology, March 19, 2013

5 The diagnostic criteria for gestational diabetes: to change or not to change? American Journal of Obstetrics and Gynecology, April 15, 2013

6 Evaluation of cytologically benign solitary thyroid nodules by ultrasonography: A retrospective analysis of 1877 cases Auris Nasus Larynx, April 10, 2013 Review Article

7 Failed Surgery in Primary Hyperparathyroidism - What has Changed with Time Experimental and Clinical Endocrinology & Diabetes, March 22, 2013

8 Autonomous Functioning Thyroid Nodules and 131I in Diagnosis and Therapy After 50 Years of Experience: What is Still Open to Debate Clinical Nuclear Medicine , April 18, 2013

9 Predominance of β-Cell Neogenesis Rather Than Replication in Humans With an Impaired Glucose Tolerance and Newly Diagnosed Diabetes Journal of Clinical Endocrinology and Metabolism, April 18, 2013

10 Nutrigenetics and Nutrigenomics of Atherosclerosis Current Atherosclerosis Reports, April 23, 2013 Review Article

11 Comparison of Diabetic Ketoacidosis in Patients With Type-1 and Type-2 Diabetes Mellitus The American Journal of the Medical Sciences, April 1, 2013

12 Prevalence of Unrecognized Diabetes Mellitus in Patients Admitted With Acute Coronary Syndrome Angiology, April 2, 2013

13 Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations The Lancet, March 26, 2013

14 Ultrasound-Based Diagnosis for Solid Thyroid Nodules with the Largest Diameter <5 mm Ultrasound in Medicine and Biology, April 12, 2013

15 Change in HbA_1c over 3 years does not improve the prediction of cardiovascular disease over and above HbA_1c measured at a single time point Diabetologia - Clinical and Experimental Diabetes and Metabolism, April 11, 2013 Review Article

16 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A_1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013

17 Inadequate Sleep as a Contributor to Obesity and Type 2 Diabetes Canadian Journal of Diabetes, April 29, 2013

18 The Effect of Insulin Infusion on the Metabolites in Cerebral Tissues Assessed With Proton Magnetic Resonance Spectroscopy in Young Healthy Subjects With High and Low Insulin Sensitivity Diabetes Care, April 19, 2013 Review Article

19 Utility of screening for diabetes in a burn center: Hemoglobin A1c, Diabetes Risk Test, or simple history? Burns, April 4, 2013 Review Article

20 Linagliptin is more effective than glimepiride at achieving a composite outcome of target HbA1c < 7% with no hypoglycaemia and no weight gain over 2 years International Journal of Clinical Practice, April 9, 2013

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Diagnostics News & Articles

Articles

Prior Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology