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Endocrinology - Diagnostics News & Articles
MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (2) Full Text Articles (99) Focus on Diabetes981 Magnetic Resonance Imaging as a Predictor of Response to Somatostatin Analogs in Acromegaly after Surgical Failure Journal of Clinical Endocrinology and Metabolism, August 30, 2010
982 High Prevalence of Normal Tests Assessing Hypercortisolism in Subjects with Mild and Episodic Cushings Syndrome Suggests that the Paradigm for Diagnosis and Exclusion of Cushings Syndrome Requires Multiple Testing Hormone and Metabolic Research, August 30, 2010
983 Sexuality Among Middle Age and Older Adults with Diagnosed and Undiagnosed Diabetes: A National, Population-Based Study Diabetes Care, August 30, 2010
984 New Diagnostic Criteria for Diabetes: Is the Change from Glucose to HbA1c Possible in All Populations? Journal of Clinical Endocrinology and Metabolism, August 27, 2010
985 Prognostic value of gated myocardial perfusion imaging for asymptomatic patients with type-2 diabetes Full Text Diabetes Care, August 26, 2010
986 Staging of Differentiated Thyroid Carcinoma Using Diagnostic 131I SPECT/CT American Journal of Roentgenology, August 25, 2010
987 Assessment of highly sensitive C-Reactive Protein levels as diagnostic discriminator of Maturity Onset Diabetes of the Young due to HNF1A mutations Full Text Diabetes Care, August 25, 2010
988 Fine needle aspiration cytology of medullary carcinoma of the thyroid with a focus on rare variants: a review of 78 cases Cytopathology, August 24, 2010
989 Insufficient sensitivity of hemoglobin A1C determination in diagnosis or screening of early diabetic states Metabolism, August 24, 2010
990 Fine-Needle Aspiration Cytology and 99mTc-pertechnetate Scintigraphy Together in Patients with Differentiated Thyroid Carcinoma Anticancer Research, August 24, 2010
991 Tumor Induced Osteomalacia: A single center experience Endocrine Practice, August 24, 2010
992 Genetic variants affecting incretin sensitivity and incretin secretion Diabetologia - Clinical and Experimental Diabetes and Metabolism, August 24, 2010
993 Cardiac function in growth hormone deficient patients before and after 1 year with replacement therapy: a magnetic resonance imaging study Pituitary, August 23, 2010
994 The Effect of Posttherapy 131I SPECT/CT on Risk Classification and Management of Patients with Differentiated Thyroid Cancer The Journal of Nuclear Medicine, August 20, 2010
995 High-Resolution Peripheral Quantitative Computed Tomographic Imaging of Cortical and Trabecular Bone Microarchitecture in Patients with Type 2 Diabetes Mellitus Journal of Clinical Endocrinology and Metabolism, August 20, 2010
996 Cystic Lymph Nodes in the Lateral Neck are an Indicator of Metastatic Papillary Thyroid Cancer Endocrine Practice, August 20, 2010
997 MicroRNA profiling of benign and malignant pheochromocytomas identifies novel diagnostic and therapeutic targets Endocrine-Related Cancer, August 20, 2010
998 Androgen deficiency in women; role of accurate testosterone measurements Maturitas, August 19, 2010
999 Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment Diabetologia - Clinical and Experimental Diabetes and Metabolism, August 19, 2010
1000 Do musculoskeletal degenerative diseases affect mortality and cause of death after 10 years in Japan? Journal of Bone and Mineral Metabolism, August 19, 2010
Clinical Pearls in Endocrinology
- Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
- The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
- Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades
Highlights in Endocrinology
Regulatory protein identified in T1DM
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryStatins increase risk of DM in postmenopausal women
As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryDetermining the basal insulin dosage in T2DM
Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summaryMost Popular Endocrinology Articles
Last month's top read Top Articles of 20121 Meaning of upper limit of normal range of post-load 1-h plasma glucose level defined by oral glucose tolerance test in Japanese subjects Journal of Diabetes Investigation, April 3, 2013 Review Article
2 Lateral Sacral Imaging in the Morbidly Obese Journal of Orthopaedic Trauma, April 24, 2013
3 Effect of sulfonylurea dose escalation on hemoglobin A1c in Veterans Affairs patients with type 2 diabetes Acta Diabetologia, April 26, 2013 Review Article
4 Effects of metformin on serum insulin and anti-mullerian hormone levels and on hyperandrogenism in patients with polycystic ovary syndrome Gynecological Endocrinology, March 19, 2013
5 The diagnostic criteria for gestational diabetes: to change or not to change? American Journal of Obstetrics and Gynecology, April 15, 2013
6 Evaluation of cytologically benign solitary thyroid nodules by ultrasonography: A retrospective analysis of 1877 cases Auris Nasus Larynx, April 10, 2013 Review Article
7 Failed Surgery in Primary Hyperparathyroidism - What has Changed with Time Experimental and Clinical Endocrinology & Diabetes, March 22, 2013
8 Autonomous Functioning Thyroid Nodules and 131I in Diagnosis and Therapy After 50 Years of Experience: What is Still Open to Debate Clinical Nuclear Medicine , April 18, 2013
9 Predominance of β-Cell Neogenesis Rather Than Replication in Humans With an Impaired Glucose Tolerance and Newly Diagnosed Diabetes Journal of Clinical Endocrinology and Metabolism, April 18, 2013
10 Nutrigenetics and Nutrigenomics of Atherosclerosis Current Atherosclerosis Reports, April 23, 2013 Review Article
11 Comparison of Diabetic Ketoacidosis in Patients With Type-1 and Type-2 Diabetes Mellitus The American Journal of the Medical Sciences, April 1, 2013
12 Prevalence of Unrecognized Diabetes Mellitus in Patients Admitted With Acute Coronary Syndrome Angiology, April 2, 2013
13 Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations The Lancet, March 26, 2013
14 Ultrasound-Based Diagnosis for Solid Thyroid Nodules with the Largest Diameter <5 mm Ultrasound in Medicine and Biology, April 12, 2013
15 Change in HbA1c over 3 years does not improve the prediction of cardiovascular disease over and above HbA1c measured at a single time point Diabetologia - Clinical and Experimental Diabetes and Metabolism, April 11, 2013 Review Article
16 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013
17 Inadequate Sleep as a Contributor to Obesity and Type 2 Diabetes Canadian Journal of Diabetes, April 29, 2013
18 The Effect of Insulin Infusion on the Metabolites in Cerebral Tissues Assessed With Proton Magnetic Resonance Spectroscopy in Young Healthy Subjects With High and Low Insulin Sensitivity Diabetes Care, April 19, 2013 Review Article
19 Utility of screening for diabetes in a burn center: Hemoglobin A1c, Diabetes Risk Test, or simple history? Burns, April 4, 2013 Review Article
20 Linagliptin is more effective than glimepiride at achieving a composite outcome of target HbA1c < 7% with no hypoglycaemia and no weight gain over 2 years International Journal of Clinical Practice, April 9, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
Other Topics in Endocrinology
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