Endocrinology - Fetal Development News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (1) Full Text Articles (40) Focus on Basic Science/Genetics

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

701 Physiologic androgen insensitivity of the fetal, neonatal, and early infantile testis is explained by the ontogeny of the androgen receptor expression in sertoli cells Full Text Journal of Clinical Endocrinology and Metabolism, August 21, 2008

702 Prognostic value of meiotic spindle imaging on fertilization rate and embryo development in in vitro-matured human oocytes Fertility and Sterility, August 15, 2008

703 Adaptive changes in neonatal hormonal and metabolic profiles induced by fetal growth restriction Full Text Journal of Clinical Endocrinology and Metabolism, August 6, 2008

704 Fetal growth restriction triggered by polycyclic aromatic hydrocarbons is associated with altered placental vasculature and AhR-dependent changes in cell death American Journal of Physiology - Endocrinology and Metabolism, August 5, 2008

705 The adrenal cortex and sexual differentiation during early human development Reviews in Endocrine and Metabolic Disease, August 4, 2008

706 Maternal nutrition, intrauterine programming and consequential risks in the offspring Reviews in Endocrine and Metabolic Disease, July 29, 2008

707 Does the Physiological Acromegaly of Pregnancy Benefit the Fetus Gynecologic and Obstetric Investigation, July 22, 2008

708 Methyl donor supplementation prevents transgenerational amplification of obesity International Journal of Obesity, July 16, 2008

709 Imaging Mass Spectrometry Reveals Unique Protein Profiles during Embryo Implantation Endocrinology, July 11, 2008

710 Diabetes Risk Begins In Utero Full Text Cell Metabolism, July 10, 2008

711 Association of Intrauterine Exposure to Maternal Diabetes and Obesity With Type 2 Diabetes in Youth Full Text Diabetes Care, July 9, 2008

712 INSL3 Levels in Second Trimester Amniotic Fluid Full Text Journal of Clinical Endocrinology and Metabolism, July 9, 2008

713 Fatal sporadic medullary carcinoma of the thyroid Endocrine Pathology, July 2, 2008

714 Zona pellucida components are present in human fetal ovary before follicle formation Molecular and Cellular Endocrinology, July 1, 2008

715 Neurodevelopmental and Neurophysiological Actions of Thyroid Hormone Journal of Neuroendocrinology, June 30, 2008

716 Prokineticin-1: A Novel Mediator of the Inflammatory Response in Third-Trimester Human Placenta Endocrinology, June 30, 2008

717 Quality of reporting of randomized controlled trials in general endocrinology literature Full Text Journal of Clinical Endocrinology and Metabolism, June 27, 2008

718 Leukemia Inhibitory Factor Regulates Trophoblast Giant Cell Differentiation via Janus Kinase 1-Signal Transducer and Activator of Transcription 3-Suppressor of Cytokine Signaling 3 Pathway Full Text Molecular Endocrinology, June 27, 2008

719 Male-like external genitalia with epididymis in a case of 46, XX disorder of sex development due to congenital adrenal hyperplasia Journal of Research in Medical Sciences, June 25, 2008

720 Amniotic fluid and umbilical cord plasma corticotropin-releasing factor (CRF), CRF-binding protein, ACTH and cortisol concentrations in intra-amniotic infection and inflammation at term Full Text Journal of Clinical Endocrinology and Metabolism, June 19, 2008

50 available pages First Previous 36 37 38 39 40 41 42 43 44 45 Next Last

Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Epigenetics of gestational diabetes mellitus and offspring health: the time for action is in early stages of life Molecular Human Reproduction, April 2, 2013

2 Treatment with the long-acting insulin analogues detemir or glargine during pregnancy in women with type 1 diabetes: comparison of glycaemic control and pregnancy outcome The Journal of Maternal-Fetal and Neonatal Medicine, April 3, 2013

3 Parental eating behavior traits are related to offspring BMI in the Quebec Family Study International Journal of Obesity, February 13, 2013

4 The diagnostic criteria for gestational diabetes: to change or not to change? American Journal of Obstetrics and Gynecology, April 15, 2013

5 Low-Carbohydrate Diet for the Treatment of Gestational Diabetes: A randomized controlled trial Diabetes Care, April 9, 2013

6 Childhood cognitive development after fetal growth restriction Ultrasound in Obstetrics & Gynecology, April 2, 2013

7 The Molecular Mechanisms of Offspring Effects from Obese Pregnancy Obesity Facts, April 4, 2013 Review Article

8 Gestational diabetes, pre-pregnancy obesity and pregnancy weight gain in relation to excess fetal growth: variations by race/ethnicity Diabetologia - Clinical and Experimental Diabetes and Metabolism, April 10, 2013 Review Article

9 Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring International Journal of Obesity, April 24, 2013 Review Article

10 Placental regulation of fetal nutrient supply Current Opinion in Clinical Nutrition & Metabolic Care, April 12, 2013 Review Article

11 Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction Hypertension in Pregnancy, March 29, 2013

12 Placental weight mediates the effects of prenatal factors on fetal growth: the extent differs by preterm status Obesity, April 18, 2013 Review Article

13 Fetal metabolic programming and epigenetic modifications: a systems biology approach Pediatric Research, March 13, 2013 Review Article

14 Effect of reducing the n-6/n-3 fatty acid ratio on the maternal and fetal leptin axis in relation to infant body composition Obesity, April 18, 2013

15 A role for mitochondria in gestational diabetes mellitus Gynecological Endocrinology, March 19, 2013

16 Risk of Childhood Obesity in the Toddler Offspring of Mothers With Gestational Diabetes Obstetrics and Gynecology, April 26, 2013 Free full text

17 Interventions designed to limit gestational weight gain: a systematic review of theory and meta-analysis of intervention components Obesity Reviews, April 17, 2013 Evidence Based Medicine Review Article

18 Risk of Childhood Obesity in the Toddler Offspring of Mothers With Gestational Diabetes Obstetrics and Gynecology, April 23, 2013

19 The obstetric syndromes: clinical relevance of placental hormones Expert Review of Endocrinology & Metabolism, March 6, 2013 Review Article

20 Influence of insulin sensitivity and secretion on glycated albumin and hemoglobin A1c in pregnant women with gestational diabetes mellitus International Journal of Gynecology & Obstetrics, April 8, 2013

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Fetal Development News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology