MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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441 Fetoscopic Fetal Transesophageal Electrocardiography: A Minimally Invasive Tool for Cardiac Monitoring, Diagnostics, and Intervention in Human Fetuses Pediatric Cardiology, February 23, 2010
442 Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development Best Practice & Research Clinical Endocrinology & Metabolism, February 23, 2010
443 Developmental programming of adult adrenal structure and steroidogenesis: effects of fetal glucocorticoid excess and postnatal dietary omega-3 fatty acids Journal of Endocrinology, February 17, 2010
444 Involvement of Pregnancy-Associated Plasma Protein-A2 in Insulin-Like Growth Factor (IGF) Binding Protein-5 Proteolysis during Pregnancy: A Potential Mechanism for Increasing IGF Bioavailability Full Text Journal of Clinical Endocrinology and Metabolism, February 16, 2010
445 Heterozygous Mutation within a Kinase-Conserved Motif of the Insulin-Like Growth Factor I Receptor Causes Intrauterine and Postnatal Growth Retardation Full Text Journal of Clinical Endocrinology and Metabolism, February 16, 2010
446 Color doppler evaluation of cerebral-umbilical pulsatility ratio and its usefulness in the diagnosis of intrauterine growth retardation and prediction of adverse perinatal outcome Full Text Indian Journal of Radiology and Imaging, February 15, 2010
447 The Influence of a High-Fat Dietary Environment in the Fetal Period on Postnatal Metabolic and Immune Function Obesity, February 15, 2010
448 Periconceptional Multivitamin Use and Infant Birth Weight Disparities Annals of Epidemiology , February 12, 2010
449 Circulating free fetal nucleic acids in maternal plasma and preeclampsia Medical Hypotheses, February 11, 2010
450 Reference range of fetal splenic circumference from 14 to 40 weeks of gestation Archives of Gynecology and Obstetrics, February 10, 2010
451 Development of the Endocardium Full Text Pediatric Cardiology, February 8, 2010
452 The Placenta: The Lost Neuroendocrine Organ NeoReviews, February 4, 2010
453 Independent effects of weight gain and fetal programming on metabolic complications in adults born small for gestational age Diabetologia - Clinical and Experimental Diabetes and Metabolism, February 2, 2010
454 Role of Early Hormonal and Nutritional Experiences in Shaping Feeding Behavior and Hypothalamic Development The Journal of Nutrition, February 1, 2010
455 Fetal programming: link between early nutrition, DNA methylation, and complex diseases Nutrition Reviews, January 29, 2010
456 Microarray analysis of placental tissue in intrauterine growth restriction Clinical Endocrinology, January 28, 2010
457 Comparing the glucose kinetics of adolescent girls and adult women during pregnancy Full Text American Journal of Clinical Nutrition, January 22, 2010
458 Change in Amniotic Fluid Levels of Multiple Anti-Angiogenic Proteins before Development of Preeclampsia and Intrauterine Growth Restriction Full Text Journal of Clinical Endocrinology and Metabolism, January 21, 2010
459 Maternal Micronutrient Deficiency, Fetal Development, and the Risk of Chronic Disease The Journal of Nutrition, January 14, 2010 Review Article
460 Fetal and neonatal thyroid function: review and summary of significant new findings Current Opinion in Endocrinology, Diabetes and Obesity, January 8, 2010 Review Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Placental regulation of fetal nutrient supply Current Opinion in Clinical Nutrition & Metabolic Care, April 12, 2013 Review Article
2 Hemoglobin A1c in Pregestational Diabetic Gravidas and the Risk of Congenital Heart Disease in the Fetus Pediatric Cardiology, May 9, 2013 Review Article
3 The Molecular Mechanisms of Offspring Effects from Obese Pregnancy Obesity Facts, April 4, 2013 Review Article
4 Maternal obesity: how big an impact does it have on offspring prenatally and during postnatal life? Expert Review of Endocrinology & Metabolism, May 17, 2013 Review Article
5 Epigenetics of gestational diabetes mellitus and offspring health: the time for action is in early stages of life Molecular Human Reproduction, April 2, 2013
6 Prepregnancy body mass index and feeding practices in relation to infants' growth The Journal for Nurse Practitioners , May 16, 2013 Free full text
7 Parental eating behavior traits are related to offspring BMI in the Quebec Family Study International Journal of Obesity, February 13, 2013
8 Fetal growth factors and fetal nutrition Seminars in Fetal and Neonatal Medicine, May 6, 2013 Review Article
9 Mild Iodine Deficiency During Pregnancy Is Associated With Reduced Educational Outcomes in the Offspring: 9-Year Follow-up of the Gestational Iodine Cohort Journal of Clinical Endocrinology and Metabolism, May 10, 2013
10 Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring International Journal of Obesity, April 24, 2013 Review Article
11 Low-Carbohydrate Diet for the Treatment of Gestational Diabetes: A randomized controlled trial Diabetes Care, April 9, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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