Peds Endocrinology News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (3) Full Text Articles (214) Focus on Diabetes

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

581 Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland Pediatric Diabetes, April 26, 2012

582 Validation of classification algorithms for childhood diabetes identified from administrative data Pediatric Diabetes, April 25, 2012

583 All glutathione forms are depleted in blood of obese and type 1 diabetic children Pediatric Diabetes, April 25, 2012

584 Early-onset, severe lipoatrophy in a patient with permanent neonatal diabetes mellitus secondary to a recessive mutation in the INS gene Pediatric Diabetes, April 25, 2012

585 Evaluation of a combined blood glucose monitoring and gaming system (Didget) for motivation in children, adolescents, and young adults with type 1 diabetes Pediatric Diabetes, April 25, 2012

586 GAD autoantibody epitope pattern after GAD-alum treatment in children and adolescents with type 1 diabetes Pediatric Diabetes, April 25, 2012

587 Genetic correlates of early accelerated infant growth associated with juvenile-onset type 1 diabetes Pediatric Diabetes, April 25, 2012

588 Disseminated Neuroendocrine Carcinoma in a Pediatric Patient: A Rare Case and Diagnostic Challenge Journal of Pediatric Hematology/Oncology, April 25, 2012

589 Cardiovascular risk in pediatric type 1 diabetes: sex-specific intima-media thickening verified by automatic contour identification and analyzing systems Pediatric Diabetes, April 24, 2012

590 Validation of a self-report version of the diabetes self-management profile Pediatric Diabetes, April 24, 2012

591 Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies Pediatric Diabetes, April 24, 2012

592 Type 2 diabetes in youth: are there racial differences in beta-cell responsiveness relative to insulin sensitivity Pediatric Diabetes, April 24, 2012

593 Creating a national register of childhood type 1 diabetes using routinely collected hospital data Pediatric Diabetes, April 24, 2012

594 KATP channel mutations in infants with permanent diabetes diagnosed after 6 months of life Pediatric Diabetes, April 24, 2012

595 The glucokinase mutation p.T206P is common among MODY patients of Jewish Ashkenazi descent Pediatric Diabetes, April 24, 2012

596 Incidence, genetics, and clinical phenotype of permanent neonatal diabetes mellitus in northwest Saudi Arabia Pediatric Diabetes, April 24, 2012

597 Partial ABCC8 gene deletion mutations causing diazoxide-unresponsive hyperinsulinaemic hypoglycaemia Pediatric Diabetes, April 24, 2012

598 Evaluation of 1,5-anhydroglucitol, hemoglobin A1c, and glucose levels in youth and young adults with type 1 diabetes and healthy controls Pediatric Diabetes, April 20, 2012

599 Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes Pediatric Diabetes, April 20, 2012

600 The convergence of type 1 and type 2 diabetes in childhood The accelerator hypothesis Pediatric Diabetes, April 20, 2012

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

2 The Challenge of Growth Hormone Deficiency Diagnosis and Treatment during the Transition from Puberty into Adulthood Frontiers in Endocrinology, March 26, 2013 Review Article

3 Racial/ethnic Differences in Clinical and Biochemical Type 2 Diabetes Mellitus Risk Factors in Children Obesity, April 18, 2013 Review Article

4 Diabetic ketoacidosis at the onset of type 1 diabetes is associated with future HbA_1c levels Diabetologia - Clinical and Experimental Diabetes and Metabolism, April 16, 2013 Review Article

5 Factors Associated With Microalbuminuria in 7,549 Children and Adolescents With Type 1 Diabetes in the T1D Exchange Clinic Registry Diabetes Care, April 24, 2013 Review Article

6 Increasing body mass index, blood pressure, and acanthosis nigricans abnormalities in school-age children The Journal of School Nursing, April 22, 2013

7 Urinary Bisphenol A and Obesity in US Children American Journal of Epidemiology, April 9, 2013 Review Article

8 The Relationship Between Vitamin D Status and Adrenal Insufficiency in Critically Ill Children Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article

9 Effects of Recombinant Human Growth Hormone for 1 Year on Body Composition and Muscle Strength in Children on Long-Term Steroid Therapy: Randomized Controlled, Delayed-Start Study Journal of Clinical Endocrinology and Metabolism, April 29, 2013

10 Risk of Childhood Obesity in the Toddler Offspring of Mothers With Gestational Diabetes Obstetrics and Gynecology, April 23, 2013

11 Thyroid Cancer in Pediatric Age Group: An Institutional Experience and Review of the Literature Journal of Pediatric Hematology/Oncology, February 22, 2013 Review Article

12 A structured educational insulin pump therapy programme: the views of children/young people and their parents European Diabetes Nursing, March 18, 2013

13 Omega-3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents Pediatric Diabetes, March 1, 2013 Review Article

14 Impact of vitamin D fortified milk supplementation on vitamin D status of healthy school children aged 10-14 years Osteoporosis International, March 15, 2013

15 Modelling obesity outcomes: reducing obesity risk in adulthood may have greater impact than reducing obesity prevalence in childhood Obesity Reviews, April 22, 2013 Review Article

16 Differentiating disordered affect in children and adolescents with type 1 diabetes Journal of Affective Disorders, March 28, 2013

17 Does Regular Breakfast Cereal Consumption Help Children and Adolescents Stay Slimmer? A Systematic Review and Meta-Analysis Obesity Facts, March 4, 2013 Evidence Based Medicine Review Article

18 The cost-effectiveness of a successful community-based obesity prevention program; The Be Active Eat Well Program Obesity, April 1, 2013

19 Gastric Emptying of Solids and Its Relationship with Microalbuminuria in Children and Adolescents with Type 1 Diabetes Mellitus Journal of Diabetes, April 3, 2013

20 Challenges, strategies, and gender relations among parents of children recently diagnosed with type 1 diabetes Journal of Family Nursing, April 16, 2013

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Peds Endocrinology News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology