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Peds Endocrinology News & Articles
MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (4) Full Text Articles (214) Focus on Reproduction381 Unawareness of the Effects of Soy Intake on the Management of Congenital Hypothyroidism Pediatrics, September 17, 2012
382 Differences in insulin resistance markers between children born small for gestational age or born preterm appropriate for gestational age Acta Pediatrica, September 14, 2012
383 Thyroid Function Tests in Obese Prepubertal Children: Correlations with Insulin Sensitivity and Body Fat Distribution Hormone Research in Paediatrics, September 14, 2012
384 Estimated Insulin Sensitivity and Cardiovascular Disease Risk Factors in Adolescents with and without Type 1 Diabetes The Journal of Pediatrics, September 13, 2012
385 Metabolic outcomes in young children with type 1 diabetes differ between treatment centers: the Hvidoere Study in Young Children 2009 Pediatric Diabetes, September 13, 2012
386 Variation between countries in the frequency of diabetic ketoacidosis at first presentation of type 1 diabetes in children: a systematic review Diabetologia - Clinical and Experimental Diabetes and Metabolism, September 13, 2012 Evidence Based Medicine
387 Triple specificity of ZnT8 autoantibodies in relation to HLA and other islet autoantibodies in childhood and adolescent type 1 diabetes Pediatric Diabetes, September 13, 2012
388 Efficacy of Metabolic and Psychological Screening for Mood Disorders Among Children With Type 1 Diabetes Diabetes Care, September 11, 2012 Clinical Article
389 Association of maternal diabetes and child asthma Pediatric Pulmonology, September 11, 2012
390 Surveillance following head, neck, and chest radiotherapy: Thyroid ultrasound monitoring for secondary thyroid malignancy Pediatric Blood & Cancer, September 11, 2012
391 A pediatric diabetes toolbox for creating centres of reference Pediatric Diabetes, September 10, 2012
392 Recommendations for age-appropriate education of children and adolescents with diabetes and their parents in the European Union Pediatric Diabetes, September 10, 2012
393 Technical solution for data collection, data safety and data privacy legislation: experiences from the SWEET study Pediatric Diabetes, September 10, 2012
394 Ascorbic acid blocks hyperglycemic impairment of endothelial function in adolescents with type 1 diabetes Pediatric Diabetes, September 7, 2012
395 Incidence of type 1 and type 2 diabetes in youth in the US Virgin Islands, 2001-2010 Pediatric Diabetes, September 7, 2012
396 Epidemiology of hyperglycemic hyperosmolar syndrome in children hospitalized in USA Pediatric Diabetes, September 7, 2012
397 Harmonize care to optimize outcome in children and adolescents with diabetes mellitus: treatment recommendations in Europe Pediatric Diabetes, September 7, 2012
398 Heterogeneity in the systems of pediatric diabetes care across the European Union Pediatric Diabetes, September 7, 2012
399 Type I diabetes among children and young adults: the role of country of birth, socioeconomic position and sex Pediatric Diabetes, September 7, 2012
400 Neonatal Hyperbilirubinemia in the Low-Intermediate–Risk Category on the Bilirubin Nomogram Pediatrics, September 7, 2012
Clinical Pearls in Endocrinology
- Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
- The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
- Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades
Highlights in Endocrinology
Regulatory protein identified in T1DM
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryStatins increase risk of DM in postmenopausal women
As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryDetermining the basal insulin dosage in T2DM
Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summaryMost Popular Endocrinology Articles
Last month's top read Top Articles of 20121 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013
2 The Challenge of Growth Hormone Deficiency Diagnosis and Treatment during the Transition from Puberty into Adulthood Frontiers in Endocrinology, March 26, 2013 Review Article
3 Racial/ethnic Differences in Clinical and Biochemical Type 2 Diabetes Mellitus Risk Factors in Children Obesity, April 18, 2013 Review Article
4 Diabetic ketoacidosis at the onset of type 1 diabetes is associated with future HbA1c levels Diabetologia - Clinical and Experimental Diabetes and Metabolism, April 16, 2013 Review Article
5 Factors Associated With Microalbuminuria in 7,549 Children and Adolescents With Type 1 Diabetes in the T1D Exchange Clinic Registry Diabetes Care, April 24, 2013 Review Article
6 Increasing body mass index, blood pressure, and acanthosis nigricans abnormalities in school-age children The Journal of School Nursing, April 22, 2013
7 Urinary Bisphenol A and Obesity in US Children American Journal of Epidemiology, April 9, 2013 Review Article
8 The Relationship Between Vitamin D Status and Adrenal Insufficiency in Critically Ill Children Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article
9 Effects of Recombinant Human Growth Hormone for 1 Year on Body Composition and Muscle Strength in Children on Long-Term Steroid Therapy: Randomized Controlled, Delayed-Start Study Journal of Clinical Endocrinology and Metabolism, April 29, 2013
10 Risk of Childhood Obesity in the Toddler Offspring of Mothers With Gestational Diabetes Obstetrics and Gynecology, April 23, 2013
11 Thyroid Cancer in Pediatric Age Group: An Institutional Experience and Review of the Literature Journal of Pediatric Hematology/Oncology, February 22, 2013 Review Article
12 A structured educational insulin pump therapy programme: the views of children/young people and their parents European Diabetes Nursing, March 18, 2013
13 Omega-3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents Pediatric Diabetes, March 1, 2013 Review Article
14 Impact of vitamin D fortified milk supplementation on vitamin D status of healthy school children aged 10-14 years Osteoporosis International, March 15, 2013
15 Modelling obesity outcomes: reducing obesity risk in adulthood may have greater impact than reducing obesity prevalence in childhood Obesity Reviews, April 22, 2013 Review Article
16 Differentiating disordered affect in children and adolescents with type 1 diabetes Journal of Affective Disorders, March 28, 2013
17 Does Regular Breakfast Cereal Consumption Help Children and Adolescents Stay Slimmer? A Systematic Review and Meta-Analysis Obesity Facts, March 4, 2013 Evidence Based Medicine Review Article
18 The cost-effectiveness of a successful community-based obesity prevention program; The Be Active Eat Well Program Obesity, April 1, 2013
19 Gastric Emptying of Solids and Its Relationship with Microalbuminuria in Children and Adolescents with Type 1 Diabetes Mellitus Journal of Diabetes, April 3, 2013
20 Challenges, strategies, and gender relations among parents of children recently diagnosed with type 1 diabetes Journal of Family Nursing, April 16, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
Other Topics in Endocrinology
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