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Reproductive Endocrinology News & Articles
MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Endocrinology
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Articles
Latest Full Text Articles (142) Focus on Atherosclerosis541 Effect of the Timing of Weight Cycling During Adulthood on Mortality Risk in Overweight and Obese Postmenopausal Women Obesity, July 15, 2011
542 Comparison of Hemoglobin A1c With Fasting Plasma Glucose and 2-h Postchallenge Glucose for Risk Stratification Among Women With Recent Gestational Diabetes Mellitus Full Text Diabetes Care, July 14, 2011
543 Development and evaluation of a standardized registry for diabetes in pregnancy using data from the Northern, North West and East Anglia regional audits Diabetic Medicine, July 11, 2011
544 Low Free Testosterone Levels Are Associated With All-Cause and Cardiovascular Mortality in Postmenopausal Diabetic Women Full Text Diabetes Care, July 8, 2011
545 Antithyroid Antibodies And Parity: Further Evidence For Microchimerism In Autoimmune Thyroid Disease American Journal of Obstetrics and Gynecology, July 7, 2011
546 Effect of Obesity on Oocyte and Embryo Quality in Women Undergoing In Vitro Fertilization Obstetrics and Gynecology, July 1, 2011
547 Treating mild gestational diabetes mellitus: a cost-effectiveness analysis American Journal of Obstetrics and Gynecology, June 28, 2011
548 The Women's Health Initiative: The Food Environment, Neighborhood Socioeconomic Status, BMI, and Blood Pressure Obesity, June 28, 2011
549 Changes in insulin resistance indicators, IGFs, and adipokines in a year-long trial of aerobic exercise in postmenopausal women Endocrine-Related Cancer, June 23, 2011
550 Polycystic ovary syndrome is associated with atherogenic changes in lipoprotein particle number and size independent of body weight Clinical Endocrinology, June 23, 2011
551 Differences in bone microarchitecture between postmenopausal Chinese-American and white women Journal of Bone and Mineral Research, June 22, 2011
552 Insulin glargine: Use during pregnancy Endocrine Practice, June 17, 2011
553 Decreased fetal cardiac performance in the first trimester correlates with hyperglycemia in pre-gestational maternal diabetes Ultrasound in Obstetrics & Gynecology, June 16, 2011
554 Mitochondrial DNA copy number in peripheral blood in polycystic ovary syndrome Metabolism, June 16, 2011
555 The impact of obesity on egg quality Journal of Assisted Reproduction and Genetics, June 13, 2011 Review Article
556 The diabetic pregnancy and offspring BMI in childhood: a systematic review and meta-analysis Diabetologia - Clinical and Experimental Diabetes and Metabolism, June 10, 2011 Evidence Based Medicine
557 The differential relationship between fat mass and bone mineral density by gender and menopausal status Journal of Bone and Mineral Metabolism, June 10, 2011
558 Pregravid cardiometabolic risk profile and risk for gestational diabetes mellitus American Journal of Obstetrics and Gynecology, June 9, 2011
559 The Expression and Regulation of Adrenomedullin in the Human Endometrium: A Candidate for Endometrial Repair Endocrinology, June 9, 2011
560 Significance of (sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review Full Text Human Reproduction Update, June 8, 2011 Evidence Based Medicine
Clinical Pearls in Endocrinology
- Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
- The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
- Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades
Highlights in Endocrinology
Regulatory protein identified in T1DM
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryStatins increase risk of DM in postmenopausal women
As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryDetermining the basal insulin dosage in T2DM
Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summaryMost Popular Endocrinology Articles
Last month's top read Top Articles of 20121 Preconception TSH and Pregnancy outcomes in Women with Hypothyroidism Endocrine Practice, March 20, 2013
2 Sexual dysfunction assessment and hormonal correlations in patients with polycystic ovary syndrome International Journal of Impotence Research: The Journal of Sexual Medicine, February 15, 2013 Review Article
3 Metabolic inflexibility is a feature of women with polycystic ovary syndrome and is associated with both insulin resistance and hyperandrogenism Journal of Clinical Endocrinology and Metabolism, April 18, 2013 Review Article
4 Metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy polycystic ovary syndrome (MU-PCOS): a comparative analysis of four simple methods useful for metabolic assessment Human Reproduction, April 22, 2013
5 The role of TGF-β in polycystic ovary syndrome Reproductive Sciences, April 22, 2013
6 Low-Carbohydrate Diet for the Treatment of Gestational Diabetes: A randomized controlled trial Diabetes Care, April 9, 2013
7 Is Insulin Resistance an Intrinsic Defect in Asian Polycystic Ovary Syndrome? Yonsei Medical Journal, April 19, 2013 Free full text
8 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013
9 Risk of Childhood Obesity in the Toddler Offspring of Mothers With Gestational Diabetes Obstetrics and Gynecology, April 23, 2013
10 Predictors of large and small for gestational age birthweight in offspring of women with gestational diabetes mellitus Diabetic Medicine, April 5, 2013
11 Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome: a cross-sectional study Fertility and Sterility, April 11, 2013
12 Pregnancy Glycemia in Mexican-American Women Without Diabetes or Gestational Diabetes and Programming for Childhood Obesity American Journal of Epidemiology, April 3, 2013 Review Article
13 Skeletal Muscle Abnormalities in Girls and Adolescents with Turner Syndrome Journal of Clinical Endocrinology and Metabolism, April 4, 2013 Review Article
14 Treatment with the long-acting insulin analogues detemir or glargine during pregnancy in women with type 1 diabetes: comparison of glycaemic control and pregnancy outcome The Journal of Maternal-Fetal and Neonatal Medicine, April 3, 2013
15 Thyroid autoimmunity and obstetric outcomes in women with recurrent miscarriage: a case control study Endocrine Connections, April 3, 2013 Review Article
16
The clinical significance and primary determinants of hirsutism in patients with the polycystic ovary syndrome
European Journal of Endocrinology, April 8, 2013
Exclusive Author Commentary
17 Anxiety, cognitive and depressive assessment in adolescents with polycystic ovarian syndrome: a pilot study Journal of Pediatric and Adolescent Gynecology , April 18, 2013
18 Chemopreventive effects of metformin on obesity-associated endometrial proliferation American Journal of Obstetrics and Gynecology, April 26, 2013
19 The use of insulin analogues in pregnancy Diabetes, Obesity and Metabolism, March 15, 2013 Review Article
20 Gestational weight loss and perinatal outcomes in overweight and obese women subsequent to diagnosis of gestational diabetes mellitus Obesity, April 25, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
Other Topics in Endocrinology
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