Neuroendocrinology News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (3) Full Text Articles (117) Focus on Pediatrics

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Prevalence of olfactory and other developmental anomalies in patients with central hypogonadotropic hypogonadism Frontiers in Endocrinology, June 19, 2013 Review Article

2 A novel mutation (P236S) in the succinate dehydrogenase subunit B gene in a Japanese patient with a posterior mediastinal paraganglioma Endocrine Pathology, June 19, 2013

3 Primary neuroendocrine carcinoma of the vagina with coexistent atypical vaginal adenosis: A rare entity Journal of Cancer Research and Therapeutics, June 19, 2013

Prior Articles

4 Pancreatic surgery with vascular reconstruction in patients with locally advanced pancreatic neuroendocrine tumors Journal of Gastrointestinal Surgery, June 18, 2013 Review Article

5 Metastases from neuroendocrine tumors to the breast are more common than previously thought. a diagnostic pitfall? World Journal of Surgery, June 18, 2013 Review Article

6 Hypothalamic involvement predicts cognitive performance and psychosocial health in long term survivors of childhood craniopharyngioma Journal of Clinical Endocrinology and Metabolism, June 17, 2013 Clinical Article

7 Functional domains of androgen receptor coactivator p44/mep50/wdr77and its interaction with smad1 PLOS ONE, June 17, 2013 Review Article

8 Pituitary-adrenal function after prolonged glucocorticoid therapy for systemic inflammatory disorders: an observational study Journal of Clinical Endocrinology and Metabolism, June 13, 2013 Clinical Article

9 Male prolactinomas presenting with normal testosterone levels Pituitary, June 13, 2013 Clinical Article

10 Increased carotid intima media thickness is associated with prolactin levels in subjects with untreated prolactinoma: a pilot study Pituitary, June 13, 2013 Review Article

11 A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Metastatic Neuroendocrine Tumor of the Pancreas Detected by 68Ga-DOTANOC and 18F-FDG PET/CT Clinical Nuclear Medicine , June 13, 2013

12 Pancreatic neuroendocrine tumor in a child with a tuberous sclerosis complex 2 (TSC2) mutation Endocrine Practice, June 12, 2013

13 Primary neuroendocrine carcinoma of the appendix: a case report and review of the literature Anticancer Research, June 12, 2013

14 Diagnostic and therapeutic role of endoscopy in gastroenteropancreatic neuroendocrine neoplasms Digestive and Liver Diseases, June 11, 2013 Review Article

15 Adult pituitary cell maintenance: lineage-specific contribution of self-duplication Molecular Endocrinology, June 11, 2013 Review Article

16 Growth hormone-releasing hormone-producing pancreatic neuroendocrine tumor in a multiple endocrine neoplasia type 1 family with an uncommon phenotype European Journal of Gastroenterology & Hepatology, June 10, 2013 Review Article

17 High variability in baseline urinary free cortisol values in patients with Cushings disease Clinical Endocrinology, June 10, 2013 Clinical Article

18 Staging accuracy of MR for pancreatic neuroendocrine tumor and imaging findings according to the tumor grade Abdominal Imaging , June 6, 2013 Review Article

19 The effect of the ANKK1/DRD2 Taq1A polymorphism on weight changes of dopaminergic treatment in prolactinomas Pituitary, June 6, 2013 Review Article

20 Peptide receptor radionuclide therapy in a patient with disabling non-functioning pituitary adenoma Pituitary, June 6, 2013

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Prognostic value of plasma neuroendocrine biomarkers in patients with acute ischemic stroke Journal of Neuroendocrinology, May 24, 2013 Review Article

2 Update: Idiopathic Adult Growth Hormone Deficiency Journal of Clinical Endocrinology and Metabolism, April 5, 2013

3 Consensus Guidelines for the Management and Treatment of Neuroendocrine Tumors Pancreas, May 3, 2013 Review Article

4 Hypothalamitis: a diagnostic and therapeutic challenge Pituitary, May 10, 2013

5 Quality of Life and Other Outcomes in Children Treated for Cushing Syndrome Journal of Clinical Endocrinology and Metabolism, May 3, 2013 Review Article

6 Clinical usefulness of plasma chromogranin a in pancreatic neuroendocrine neoplasm Journal of Korean Medical Science, May 23, 2013 Free full text Review Article

7 Humoral hypercalcemia of malignancy caused by parathyroid hormone-related peptide-secreting neuroendocrine tumors: Report of six cases Pancreatology, May 29, 2013 Review Article

8 Evaluation of clinical hypothyroidism risk due to irradiation of thyroid and pituitary glands in radiotherapy of nasopharyngeal cancer patients Journal of Medical Imaging and Radiation Oncology, May 17, 2013

9 Prevalence of cerebral aneurysm in patients with acromegaly Pituitary, May 21, 2013 Review Article

10 The prevalence and natural history of pituitary haemorrhage in prolactinoma Journal of Clinical Endocrinology and Metabolism, April 15, 2013

11 Sunitinib-induced hyperammonaemia in a patient with pancreatic neuroendocrine tumour Journal of Clinical Pharmacy and Therapeutics, April 22, 2013

12 Diagnostic performance of salivary cortisol in the diagnosis of Cushing's syndrome, adrenal incidentaloma and adrenal insufficiency European Journal of Endocrinology, April 24, 2013 Review Article

13 Cognition in perimenopause: the effect of transition stage Menopause, April 29, 2013

14 The GLP-1 receptor in the brain: role in neuroendocrine control of energy metabolism and treatment target for obesity Journal of Neuroendocrinology, May 3, 2013 Review Article

15 United States-based practice patterns and resource utilization in advanced neuroendocrine tumor treatment World Journal of Gastroenterology, May 7, 2013 Free full text

16 The Role of Thyroid Hormone on Functional Organization in the Cerebellum The Cerebellum, May 3, 2013 Review Article

17 Short-term treatment with cabergoline can lead to tumor shrinkage in patients with nonfunctioning pituitary adenomas Pituitary, May 21, 2013 Review Article

18 Higher doses of cabergoline further improve metabolic parameters in patients with prolactinoma regardless of the degree of reduction in prolactin levels Clinical Endocrinology, March 29, 2013

19 Relapsing, remitting hypercortisolism in Cushings disease due to intratumoral hemorrhages in pituitary microadenoma Journal of Clinical Neuroscience, April 25, 2013

20 Hyperglycemia promotes cerebral barrier dysfunction through activation of protein kinase C-β Diabetes, Obesity and Metabolism, May 7, 2013

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Neuroendocrinology News & Articles

Articles

Prior Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology