MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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1 Systolic Blood Pressure and Cardiovascular Outcomes During Treatment of Hypertension American Journal of Medicine, May 24, 2013 Evidence Based Medicine Clinical Article
2 MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: Functional and therapeutic implications for gene expression and the pathogenesis of hypertension Human Molecular Genetics, May 24, 2013 Review Article
3 Integrated proteomics pipeline yields novel biomarkers for predicting preeclampsia Hypertension, May 23, 2013 Review Article
4 Correlates of isolated nocturnal hypertension and target organ damage in a population-based cohort of African Americans: the jackson heart study American Journal of Hypertension, May 23, 2013 Clinical Article
5 Factors Associated with Prevalence, Awareness, Treatment and Control of Hypertension among Adults in Southern China: A Community-Based, Cross-Sectional Survey PLOS ONE, May 17, 2013 Evidence Based Medicine
6 Urinary Magnesium Excretion and Risk of Hypertension Hypertension, May 16, 2013 Clinical Article
7 Changes in Sodium Levels in Processed and Restaurant Foods, 2005 to 2011 JAMA Internal Medicine, May 15, 2013 Evidence Based Medicine Clinical Article
8 Hypertension: Role of renal ACE in response to hypertensive stimuli Nature Reviews Nephrology, May 15, 2013 Review Article
9 Blood pressure levels but not hypertensive complications have increased in Type1 diabetes pregnancies during 1989-2010 Diabetic Medicine, May 14, 2013 Clinical Article
10 The association between overall survival of prostate cancer patients and hypertension, hyperglycemia, and overweight in Southern China: a prospective cohort study Journal of Cancer Research & Clinical Oncology, May 14, 2013 Clinical Article
11 Prevention and treatment of postpartum hypertension Cochrane Reviews, May 14, 2013 Evidence Based Medicine Clinical Article
12 Long-term visit-to-visit office blood pressure variability increases the risk of adverse cardiovascular outcomes in patients with chronic kidney disease Kidney International, May 14, 2013 Clinical Article
13 The Role of Home Blood Pressure Telemonitoring in Managing Hypertensive Populations Current Hypertension Reports, May 14, 2013 Review Article
14 Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension Journal of the American Society of Nephrology, May 13, 2013
15 The contribution of preintervention blood pressure, VO2max, BMI, autonomic function and gender to exercise-induced changes in heart rate variability British Journal of Sports Medicine, May 13, 2013 Evidence Based Medicine
16 Effects of multicomponent lifestyle modification on blood pressure control in health centers: Design of the study Journal of Research in Medical Sciences, May 10, 2013 Evidence Based Medicine
17 Tianma Gouteng Yin as Adjunctive Treatment for Essential Hypertension: A Systematic Review of Randomized Controlled Trials Full Text Evidence-based Complementary and Alternative Medicine , May 9, 2013 Clinical Article
18 Effect of longer-term modest salt reduction on blood pressure Cochrane Reviews, May 9, 2013 Evidence Based Medicine Clinical Article
19 Androgen-Sensitive Hypertension Associates with Upregulated Vascular CYP4A12-20-HETE Synthase Journal of the American Society of Nephrology, May 9, 2013 Review Article
20 Clinical Correlates of Ambulatory BP Monitoring among Patients with CKD Clinical Journal of the American Society of Nephrology, May 9, 2013 Clinical Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summaryIndexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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