MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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521 Hitting the target: where do molecularly targeted therapies fit in the treatment scheduling of neuroendocrine tumours Endocrine-Related Cancer, June 11, 2012
522 Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway Endocrine-Related Cancer, June 11, 2012
523 Genetic characterization of large parathyroid adenomas Endocrine-Related Cancer, June 11, 2012
524 Is 68Ga-DOTA-NOC PET/CT indicated in patients with clinical, biochemical or radiological suspicion of neuroendocrine tumour? European Journal of Nuclear Medicine & Molecular Imaging, June 7, 2012 Clinical Article
525 Highlighting nuclear membrane staining in thyroid neoplasms with emerin: Review and diagnostic utility Diagnostic Cytopathology, June 6, 2012
526 Symptomatic or Progressive Medullary Thyroid Cancer in Patients with Unresectable Locally Advanced or Metastatic Disease Full Text Clinical Cancer Research, June 5, 2012 Clinical Article
527 Prevalence of atrial fibrillation in patients taking TSH suppression therapy for management of thyroid cancer Clinical and Investigative Medicine, June 5, 2012
528 Sellar meningiomas: an endocrinologic perspective Pituitary, June 5, 2012
529 Papillary thyroid microcarcinoma: clinicopathological characteristics and implications for treatment in 276 patients European Journal of Clinical Investigation, June 4, 2012
530 Hepatic Artery Embolization for Neuroendocrine Tumors: Postprocedural Management and Complications Full Text The Oncologist, June 1, 2012
531 The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells Endocrine-Related Cancer, May 31, 2012
532 First Experience With Proteasome Inhibitor Treatment of Radioiodine Nonavid Thyroid Cancer Using Bortezomib Clinical Nuclear Medicine , May 30, 2012 Clinical Article
533 Percutaneous Osteoplasty Combined With Radioiodine Therapy as a Treatment for Bone Metastasis Developing After Differentiated Thyroid Carcinoma Clinical Nuclear Medicine , May 25, 2012 Clinical Article
534 131I SPECT/CT in the Follow-Up of Patients With Differentiated Thyroid Carcinoma Clinical Nuclear Medicine , May 25, 2012
535 Pheochromocytoma in Multiple Endocrine Neoplasia Type 2A: Positive 123I MIBG With Negative CT and Equivocal 131I MIBG Imaging Clinical Nuclear Medicine , May 25, 2012
536 Preablation Stimulated Thyroglobulin Is a Good Predictor of Successful Ablation in Patients With Differentiated Thyroid Cancer Clinical Nuclear Medicine , May 24, 2012 Clinical Article
537 Simulation of Post-Thyroidectomy Treatment Alternatives for Triiodothyronine or Thyroxine Replacement in Pediatric Thyroid Cancer Patients Thyroid, May 24, 2012
538 Detection of Subcentimeter Metastatic Cervical Lymph Node by 18F-FDG PET/CT in Patients With Well-Differentiated Thyroid Carcinoma and High Serum Thyroglobulin But Negative 131I Whole-Body Scan Clinical Nuclear Medicine , May 24, 2012 Clinical Article
539 Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmo Diet and Cancer Study cardiovascular cohort International Journal of Obesity, May 23, 2012
540 Development of a Multidisciplinary, Multicampus Subspecialty Practice in Endocrine Cancers Journal of Oncology Practice, May 22, 2012
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Clinical implication of the BRAFV600E mutation in papillary thyroid carcinoma World Journal of Surgical Oncology, May 21, 2013 Free full text Review Article
2 Hyperthyroidism and Thyroid Cancer Risk: A Population-based Cohort Study Experimental and Clinical Endocrinology & Diabetes, April 29, 2013
3 Advanced medullary thyroid cancer: pathophysiology and management Cancer Management and Research, May 13, 2013 Free full text
4 Progress in molecular-based management of differentiated thyroid cancer The Lancet, April 17, 2013
5 United States-based practice patterns and resource utilization in advanced neuroendocrine tumor treatment World Journal of Gastroenterology, May 7, 2013 Free full text
6 The Clinical and Economic Burden of a Sustained Increase in Thyroid Cancer Incidence Cancer Epidemiology, Biomarkers & Prevention, May 17, 2013 Review Article
7 Differentiated thyroid carcinoma: defining new paradigms for the post-operative management Endocrine-Related Cancer, April 11, 2013 Review Article
8 Hemodialysis in patients requiring 131I treatment for thyroid carcinoma The International Journal of Artificial Organs, May 9, 2013
9 Association between braf v600e mutation and mortality in patients with papillary thyroid cancer JAMA, April 26, 2013
10 2013 European Thyroid Association Guidelines for the Diagnosis and Treatment of Thyrotropin-Secreting Pituitary Tumors European Thyroid Journal, May 7, 2013
11 Percutaneous Laser Ablation of Metastatic Lymph Nodes in the Neck From Papillary Thyroid Carcinoma: Preliminary Results Journal of Clinical Endocrinology and Metabolism, May 13, 2013
12 Impact of lymph node ratio on survival in papillary thyroid cancer Annals of Surgical Oncology, May 28, 2013
13 Preoperative and Postoperative 18FDG PET/CT and Bone Scintigraphy Images in a Patient With Parathyroid Adenoma Clinical Nuclear Medicine , May 21, 2013
14 Could 18F-FDG-PET/CT avoid unnecessary thyroidectomies in patients with cytological diagnosis of follicular neoplasm Langenbeck's Archives of Surgery, May 3, 2013
15
Unbalanced estrogen metabolism in thyroid cancer
International Journal of Cancer, May 20, 2013
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16 Endosonographic and cyst fluid characteristics of cystic pancreatic neuroendocrine tumours: A multicentre case series Digestive and Liver Diseases, April 15, 2013
17 Cytopathological review of patients that underwent thyroidectomies based on the diagnosis of papillary thyroid carcinoma by fine needle aspiration cytology but were later found to have benign tumors by histopathology Surgery Today, May 21, 2013 Review Article
18 Fasting proinsulin levels are significantly associated with 20 year cancer mortality rates Diabetologia - Clinical and Experimental Diabetes and Metabolism, May 1, 2013 Review Article
19 Diabetes And Cancer: Two Diseases With Obesity As A Common Risk Factor Diabetes, Obesity and Metabolism, May 14, 2013 Review Article
20 Central lymph node dissection in patients with papillary thyroid cancer: a population level analysis of 14,257 cases The American Journal of Surgery, March 6, 2013 Review Article
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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