Endocrinology - Diabetes News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

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121 Osteopathic manual treatment in patients with diabetes mellitus and comorbid chronic low back pain: subgroup results from the osteopathic trial Journal of the American Osteopathic Association, June 11, 2013 Clinical Article

122 Association between hypoglycemia and dementia in a biracial cohort of older adults with diabetes mellitus JAMA Internal Medicine, June 11, 2013 Evidence Based Medicine Clinical Article

123 Intensity of peri-operative glycemic control and postoperative outcomes in patients with diabetes: a meta-analysis Diabetes Research and Clinical Practice, June 11, 2013 Evidence Based Medicine Review Article

124 Application of speckle-tracking in the evaluation of carotid artery function in subjects with hypertension and diabetes Journal of the American Society of Echocardiography, June 11, 2013 Clinical Article

125 Increased electrical nerve stimulation threshold of the sciatic nerve in patients with diabetic foot gangrene: a prospective parallel cohort study European Journal of Anaesthesiology, June 11, 2013 Clinical Article

126 Racial differences in HbA_1c: A cross-sectional analysis of a Brazilian public primary care population Primary Care Diabetes, June 11, 2013 Clinical Article

127 Prevalence of monogenic diabetes in the population-based Norwegian Childhood Diabetes Registry Diabetologia - Clinical and Experimental Diabetes and Metabolism, June 11, 2013 Review Article

128 Influence of macro- and microvascular comorbidity on time to insulin initiation in type 2 diabetes patients: A retrospective database analysis in Germany, France, and UK Primary Care Diabetes, June 11, 2013 Clinical Article

129 Impact of diabetes on costs before and after major lower extremity amputations in Germany Journal of Diabetes and its Complications, June 11, 2013 Review Article

130 Severe hypoglycaemia requiring emergency medical assistance by ambulance services in the East Midlands: A retrospective study Primary Care Diabetes, June 11, 2013 Clinical Article

131 A structured, group-based diabetes self-management education (DSME) programme for people, families and whanau with type 2 diabetes (T2DM) in New Zealand: An observational study Primary Care Diabetes, June 11, 2013 Clinical Article

132 Relationship between type-2 diabetes and use of metformin with risk of colorectal adenoma in an American population receiving colonoscopy Journal of Diabetes and its Complications, June 10, 2013 Clinical Article

133 Fasting glucose measurement as a potential first step screening for glucose metabolism abnormalities in women with anovulatory polycystic ovary syndrome Human Reproduction, June 10, 2013 Clinical Article

134 Comparison of normal fasting and one-hour glucose levels as predictors of future diabetes during a 34-year follow-up Annals of Medicine, June 10, 2013 Evidence Based Medicine Clinical Article

135 Lipid accumulation in overweight type 2 diabetic subjects: relationships with insulin sensitivity and adipokines Acta Diabetologia, June 10, 2013 Review Article

136 Exercise might improve cardiovascular autonomic regulation in adolescents with type 1 diabetes Acta Diabetologia, June 10, 2013 Review Article

137 Insulin resistance and risk of incident heart failure Circulation: Heart Failure, June 10, 2013 Clinical Article

138 The glucose dysmetabolism in the acute phase of non-diabetic ST-elevation myocardial infarction: from insulin resistance to hyperglycemia Acta Diabetologia, June 10, 2013 Review Article

139 Type 1 diabetes and celiac disease in adults: glycemic control and diabetic complications Acta Diabetologia, June 10, 2013 Review Article

140 Polycystic ovary syndrome is not associated with genetic variants that mark risk of type 2 diabetes Acta Diabetologia, June 10, 2013 Review Article

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Endocrinology - Diabetes News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology