MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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881 Aortic Distensibility in Type 1 Diabetes Diabetes Care, March 11, 2013 Clinical Article
882 Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease Current Opinion in Endocrinology, Diabetes and Obesity, March 11, 2013 Review Article
883 Diabetes does not affect outcome of symptomatic carotid stenosis treated with endovascular techniques European Neurology, March 11, 2013 Clinical Article
884 Efficacy, safety and dose-response relationship of teneligliptin, a dipeptidyl peptidase-4 inhibitor, in Japanese patients with type 2 diabetes mellitus Diabetes, Obesity and Metabolism, March 11, 2013 Clinical Article
885 Screening of patients with tuberculosis for diabetes mellitus in India Tropical Medicine & International Health, March 11, 2013 Evidence Based Medicine Clinical Article
886 Determinants of Maternal Triglycerides in Women With Gestational Diabetes Mellitus in the Metformin in Gestational Diabetes (MiG) Study Diabetes Care, March 8, 2013 Clinical Article
887 Complexity of the Relation Between Hemoglobin A1C, Diabetes Mellitus, and Progression of Coronary Narrowing in Postmenopausal Women The American Journal of Cardiology, March 8, 2013 Clinical Article
888 Clinical and Genetic Risk Factors for Type 2 Diabetes at Early or Late Post Partum After Gestational Diabetes Mellitus Journal of Clinical Endocrinology and Metabolism, March 8, 2013 Clinical Article
889 Dose-ranging study with the glucokinase activator AZD1656 in patients with type 2 diabetes mellitus on metformin Diabetes, Obesity and Metabolism, March 8, 2013 Clinical Article
890 Economic Costs of Diabetes in the U.S. in 2012 Diabetes Care, March 8, 2013 Review Article Clinical Article
891 Reduced Adipose Tissue Macrophage Content Is Associated With Improved Insulin Sensitivity in Thiazolidinedione-Treated Diabetic Humans Diabetes, March 8, 2013 Clinical Article
892 Efficacy and Safety of Canagliflozin in Subjects With Type 2 Diabetes And Chronic Kidney Disease Diabetes, Obesity and Metabolism, March 8, 2013 Clinical Article
893 Iron and Diabetes Risk Cell Metabolism, March 8, 2013 Clinical Article
894 An Evidence-Based and Practical Approach to Using Bydureon in Patients With Type 2 Diabetes Full Text Journal of the American Board of Family Medicine, March 8, 2013 Evidence Based Medicine
895 Prediabetes and impaired lung function in asymptomatic adults Diabetes Research and Clinical Practice, March 8, 2013 Clinical Article
896 Prospective Association of 25(OH)D with Metabolic Syndrome Clinical Endocrinology, March 8, 2013 Clinical Article
897 Associations Between Age at Menarche and Menopause With Cardiovascular Disease, Diabetes, and Osteoporosis in Chinese Women Journal of Clinical Endocrinology and Metabolism, March 8, 2013 Clinical Article
898 A Nonsense Polymorphism (R392X) in TLR5 Protects from Obesity but Predisposes to Diabetes The Journal of Immunology, March 8, 2013 Review Article Clinical Article
899 Insulin resistance: a major factor associated with significant liver fibrosis in Egyptian patients with genotype 4 chronic hepatitis C European Journal of Gastroenterology & Hepatology, March 8, 2013 Clinical Article
900 Significant Coronary Stenosis in Asymptomatic Chinese With Different Glycemic Status Diabetes Care, March 8, 2013 Review Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summaryIndexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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