MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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861 Association of Lipid Peroxidation with Endothelial Dysfunction in Patients with Overt Hypothyroidism Experimental and Clinical Endocrinology & Diabetes, March 12, 2013 Clinical Article
862 Do patients and physicians agree on diabetes management? A study conducted in Public Healthcare Centres in Brazil Patient Education and Counselling, March 12, 2013 Clinical Article
863 Diabetes care: can QOF miss the point? Unexpected improvement in diabetes control should prompt a search for an underlying cause Practical Diabetes, March 12, 2013
864
Establishing a registry of children and young people with diabetes in north east England and north Cumbria
Practical Diabetes, March 12, 2013
Review Article
Exclusive Author Commentary
865 Unintended consequences of delisting routine eye exams on retinopathy screening for people with diabetes in Ontario, Canada Canadian Medical Association Journal, March 12, 2013 Evidence Based Medicine
866 A case of hepatocyte nuclear factor-1β (TCF2) maturity onset diabetes of the young misdiagnosed as type 1 diabetes and unnecessarily treated with insulin Journal of Diabetes, March 12, 2013
867 Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes Cell Metabolism, March 12, 2013
868 Changes in Insulin Resistance and HbA1c Are Related to Exercise-Mediated Changes in Body Composition in Older Adults With Type 2 Diabetes: Interim outcomes from the GREAT2DO Trial Diabetes Care, March 11, 2013 Clinical Article
869 Efficacy and safety of lixisenatide in the treatment of Type 2 diabetes mellitus: a review of Phase III clinical data Expert Review of Endocrinology & Metabolism, March 11, 2013 Review Article Clinical Article
870 Short-term intensive insulin therapy in type 2 diabetes mellitus: a systematic review and meta-analysis The Lancet, March 11, 2013 Evidence Based Medicine Review Article
871 Effect of fruit restriction on glycemic control in patients with type 2 diabetes - A randomized trial Full Text Nutrition Journal, March 11, 2013 Clinical Article
872 Prediabetes Is Associated with a High-Risk Colorectal Adenoma Digestive Diseases and Sciences, March 11, 2013 Clinical Article
873 Plasma concentrations of trans fatty acids in persons with type 2 diabetes between September 2002 and April 2004 American Journal of Clinical Nutrition, March 11, 2013 Review Article
874
Medical strategies to reduce amputation in patients with Type2 diabetes
Diabetic Medicine, March 11, 2013
Clinical Article
Exclusive Author Commentary
875 Metabolic surgery for type 2 diabetes: efficacy and risks Current Opinion in Endocrinology, Diabetes and Obesity, March 11, 2013 Review Article Clinical Article
876 Mild depressive symptoms do not influence cognitive functioning in patients with type 2 diabetes Psychoneuroendocrinology, March 11, 2013 Clinical Article
877 Personal and Relationship Challenges of Adults With Type 1 Diabetes: A qualitative focus group study Diabetes Care, March 11, 2013 Review Article
878 Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study The Lancet, March 11, 2013 Clinical Article
879 Concentration and activity of the soluble form of the Interleukin-7 Receptor alpha in type I diabetes identifies an interplay between hyperglycemia and immune function Diabetes, March 11, 2013 Review Article
880 Coping and psychological distress in mothers of adolescents with type 1 diabetes Maternal and Child Health Journal , March 11, 2013 Clinical Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, April 19, 2013
2 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013
3 Management of Painful Peripheral Diabetic Neuropathy British Journal of Medical Practitioners, April 23, 2013 Free full text
4 Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes, April 24, 2013 Review Article
5 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013
6 Trends in selection and timing of first-line pharmacotherapy in older patients with Type 2 diabetes diagnosed between 1994 and 2006 Diabetic Medicine, April 18, 2013
7 Meta-Analysis of Impact of Different Types and Doses of Statins on New-Onset Diabetes Mellitus The American Journal of Cardiology, April 4, 2013 Evidence Based Medicine Review Article
8 A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review Diabetes, Obesity and Metabolism, April 4, 2013 Evidence Based Medicine Review Article
9 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013
10 Vascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial American Journal of Clinical Nutrition, April 10, 2013
11 Do thiazolidinediones still have a role in treatment of t2dm? Diabetes, Obesity and Metabolism, March 27, 2013
12 Relationships Between Serum Adiponectin and Bone Density, Adiposity and Calcified Atherosclerotic Plaque in the African American-Diabetes Heart Study Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article
13 Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies Diabetes Research and Clinical Practice, April 23, 2013 Evidence Based Medicine
14 Antihypertensive treatment in diabetic patients- Review of current data Maturitas, April 15, 2013 Review Article
15 GLP-1 Agonists in Type 1 Diabetes Clinical Immunology, April 24, 2013 Review Article
16 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GETGOAL-DUO-1) Diabetes Care, April 8, 2013
17 Effects of patient-tailored atorvastatin therapy on ameliorating the levels of atherogenic lipids and inflammation beyond lowering low-density lipoprotein cholesterol in patients with type 2 diabetes Journal of Diabetes Investigation, April 3, 2013 Review Article
18 GLP-1 and the Long-Term Outcome of Type 2 Diabetes Mellitus After Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Subjects Annals of Surgery, April 18, 2013
19 Improvement of β–cell function after achievement of optimal glycemic control via long-term continuous subcutaneous insulin infusion therapy in non-newly diagnosed type 2 diabetic patients with suboptimal glycemic control Diabetes/Metabolism Research and Reviews, April 17, 2013
20 Effect of intensive glycaemic control on endothelial progenitor cells in patients with long-standing uncontrolled type 2 diabetes European Journal of Preventive Cardiology, April 25, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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