MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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181 Detection and Characterization of Two Novel Mutations in the HNF4A Gene in Maturity-Onset Diabetes of the Young Type 1 in Two Japanese Families Hormone Research in Paediatrics, May 3, 2013 Review Article
182 Cardiovascular Complications and Mortality After Diabetes Diagnosis for South Asian and Chinese Patients: A population-based cohort study Diabetes Care, May 3, 2013 Clinical Article
183 Efficacy And Safety Of Lixisenatide Once Daily Versus Placebo In Type 2 Diabetes Insufficiently Controlled On Pioglitazone (Getgoal-P) Diabetes, Obesity and Metabolism, May 2, 2013 Clinical Article
184 Strong Parent-of-Origin Effects in the Association of KCNQ1 Variants with Type 2 Diabetes Mellitus in American Indians Diabetes, May 2, 2013 Review Article
185 The Relationship Between Diabetic Retinopathy and Cognitive Impairment Diabetes Care, May 2, 2013 Clinical Article
186 Rivoglitazone: A New Thiazolidinedione for the Treatment of Type 2 Diabetes Mellitus Annals of Pharmacotherapy, May 2, 2013 Clinical Article
187 Treatment of type 2 diabetes with saxagliptin: a pharmacoeconomic evaluation in Argentina Full Text Health Economics Review, May 2, 2013 Review Article
188 Expression of tissue inhibitor of metalloprotease 3 is reduced in ischemic but not neuropathic ulcers from patients with type 2 diabetes mellitus Acta Diabetologia, May 2, 2013 Review Article
189 Relationship between urinary bisphenol A levels and prediabetes among subjects free of diabetes Acta Diabetologia, May 2, 2013 Review Article
190 A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes Journal of Clinical Periodontology, May 2, 2013 Evidence Based Medicine
191 The effectiveness of text messages support for diabetes self-management: protocol of the TEXT4DSM study in the democratic Republic of Congo, Cambodia and the Philippines Full Text BMC Public Health, May 2, 2013 Clinical Article
192 Diabetes and periodontal diseases: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases Journal of Clinical Periodontology, May 2, 2013 Evidence Based Medicine
193 Cord Serum Lipidome in Prediction of Islet Autoimmunity and Type 1 Diabetes Diabetes, May 2, 2013 Review Article
194 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled by Established Basal Insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-l) Diabetes Care, May 1, 2013 Clinical Article
195 Quality of Care of People With Type 2 Diabetes in Eight European Countries: Findings from the Guideline Adherence to Enhance Care (GUIDANCE) study Diabetes Care, May 1, 2013 Clinical Guideline Clinical Article
196 Metabolic Signature Shift in Type 2 Diabetes Mellitus Revealed by Mass Spectrometry-based Metabolomics Journal of Clinical Endocrinology and Metabolism, May 1, 2013 Review Article
197 Overexpression of Hemopexin in the Diabetic Eye: A new pathogenic candidate for diabetic macular edema Diabetes Care, May 1, 2013 Review Article
198 Impact of diabetes on overall and cancer-specific mortality in colorectal cancer patients Journal of Cancer Research & Clinical Oncology, May 1, 2013 Clinical Article
199 Diabetes and tooth loss: An analysis of data from the National Health and Nutrition Examination Survey, 2003–2004 The Journal of the American Dental Association , May 1, 2013 Evidence Based Medicine
200 Glycemic Control Associated With Secure Patient-Provider Messaging Within a Shared Electronic Medical Record: A Longitudinal Analysis Diabetes Care, May 1, 2013 Clinical Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, April 19, 2013
2 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013
3 Management of Painful Peripheral Diabetic Neuropathy British Journal of Medical Practitioners, April 23, 2013 Free full text
4 Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes, April 24, 2013 Review Article
5 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013
6 Trends in selection and timing of first-line pharmacotherapy in older patients with Type 2 diabetes diagnosed between 1994 and 2006 Diabetic Medicine, April 18, 2013
7 Meta-Analysis of Impact of Different Types and Doses of Statins on New-Onset Diabetes Mellitus The American Journal of Cardiology, April 4, 2013 Evidence Based Medicine Review Article
8 A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review Diabetes, Obesity and Metabolism, April 4, 2013 Evidence Based Medicine Review Article
9 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013
10 Vascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial American Journal of Clinical Nutrition, April 10, 2013
11 Do thiazolidinediones still have a role in treatment of t2dm? Diabetes, Obesity and Metabolism, March 27, 2013
12 Relationships Between Serum Adiponectin and Bone Density, Adiposity and Calcified Atherosclerotic Plaque in the African American-Diabetes Heart Study Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article
13 Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies Diabetes Research and Clinical Practice, April 23, 2013 Evidence Based Medicine
14 Antihypertensive treatment in diabetic patients- Review of current data Maturitas, April 15, 2013 Review Article
15 GLP-1 Agonists in Type 1 Diabetes Clinical Immunology, April 24, 2013 Review Article
16 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GETGOAL-DUO-1) Diabetes Care, April 8, 2013
17 Effects of patient-tailored atorvastatin therapy on ameliorating the levels of atherogenic lipids and inflammation beyond lowering low-density lipoprotein cholesterol in patients with type 2 diabetes Journal of Diabetes Investigation, April 3, 2013 Review Article
18 GLP-1 and the Long-Term Outcome of Type 2 Diabetes Mellitus After Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Subjects Annals of Surgery, April 18, 2013
19 Improvement of β–cell function after achievement of optimal glycemic control via long-term continuous subcutaneous insulin infusion therapy in non-newly diagnosed type 2 diabetic patients with suboptimal glycemic control Diabetes/Metabolism Research and Reviews, April 17, 2013
20 Effect of intensive glycaemic control on endothelial progenitor cells in patients with long-standing uncontrolled type 2 diabetes European Journal of Preventive Cardiology, April 25, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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