Endocrinology - Bone Metabolism News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (8) Full Text Articles (100) Focus on Thyroid

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

41 Bisphosphonate-related osteonecrosis of the jaw in non-malignant bone disease Rheumatology International, May 9, 2013 Clinical Article

42 Analysis of the effect of various decalcification agents on the quantity and quality of nucleic acid (DNA and RNA) recovered from bone biopsies Annals of Diagnostic Pathology, May 9, 2013 Clinical Article

43 Measurement of Bone Mineral Density by Dual Energy X-ray Absorptiometry in Juvenile Idiopathic Arthritis The Indian Journal of Pediatrics, May 9, 2013 Clinical Article

44 Consumption of yogurts fortified in vitamin D and calcium reduces serum parathyroid hormone and markers of bone resorption: a double-blind randomized controlled trial in institutionalized elderly women Journal of Clinical Endocrinology and Metabolism, May 8, 2013 Clinical Article

45 Deep wound cultures and bone biopsy in diabetic foot osteomyelitis Diabetes/Metabolism Research and Reviews, May 8, 2013 Review Article

46 Diagnostic measures for sarcopenia and bone mineral density Osteoporosis International, May 8, 2013 Review Article

47 CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications Leukemia, May 8, 2013 Clinical Article

48 Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy Human Molecular Genetics, May 8, 2013 Review Article

49 Discrepancy in bone mineral densities at different skeletal sites in hip osteoarthritis patients Modern Rheumatology, May 8, 2013 Review Article

50 Osteopontin knockdown suppresses non-small cell lung cancer cell invasion and metastasis Full Text Chinese Medical Journal, May 8, 2013 Clinical Article

51 Late onset psychosis and risedronate treatment for osteoporosis Clinical Schizophrenia & Related Psychoses, May 8, 2013

52 3-year follow-up results of bone mineral content and density after a school-based physical activity randomized intervention trial Bone, May 7, 2013 Evidence Based Medicine

53 Higher serum uric acid is associated with higher bone mass, lower bone turnover, and lower prevalence of vertebral fracture in healthy postmenopausal women Osteoporosis International, May 6, 2013 Review Article

54 Prevention of steroid-induced low bone mineral density in children with renal diseases: a systematic review Nephrology Dialysis Transplantation, May 6, 2013 Evidence Based Medicine Review Article Clinical Article

55 Chronic Kidney Disease Mineral and Bone Disorders: An Evidence-Based Approach Full Text The Journal for Nurse Practitioners , May 6, 2013 Evidence Based Medicine Review Article Clinical Article

56 Trends in Hip Fracture Rates in US Hemodialysis Patients, 1993-2010 American Journal of Kidney Diseases, May 3, 2013 Clinical Article

57 The Osteocyte: An Endocrine Cell and More Endocrine Reviews, May 2, 2013 Review Article

58 A phase 3, double-blind, randomised, parallel-group, placebo-controlled study of oral weekly alendronate for the prevention of androgen deprivation bone loss in nonmetastatic prostate cancer: the cancer and osteoporosis research with alendronate and leuprolide (coral) study Full Text European Urology, May 2, 2013 Clinical Article

59 A secular increase in BMD in Chinese women Journal of Bone and Mineral Metabolism, May 2, 2013 Review Article

60 Osteochondral lesions in children with juvenile idiopathic arthritis Pediatric Rheumatology, May 2, 2013 Review Article

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 PTH replacement therapy of hypoparathyroidism Osteoporosis International, April 17, 2013 Review Article

2 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013

3 Effect of Pioglitazone on Body Composition and Bone Density in Subjects with Prediabetes in the ACT NOW Trial Diabetes, Obesity and Metabolism, April 3, 2013 Review Article

4 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

5 Vertebral bone marrow fat associated with lower trabecular BMD and prevalent vertebral fracture in older adults Journal of Clinical Endocrinology and Metabolism, April 4, 2013

6 Guidelines for the use of bone metabolic markers in the diagnosis and treatment of osteoporosis (2012 edition) Journal of Bone and Mineral Metabolism, February 5, 2013 Clinical Guideline

7 Hip bone loss is attenuated with 1000 IU but not 400 IU daily vitamin D3: a 1 year double-blind RCT in postmenopausal women Journal of Bone and Mineral Research, April 15, 2013

8 Bisphosphonates and risk of subtrochanteric, femoral shaft, and atypical femur fracture: A systematic review and meta-analysis Journal of Bone and Mineral Research, February 14, 2013 Evidence Based Medicine

9 Relationships Between Serum Adiponectin and Bone Density, Adiposity and Calcified Atherosclerotic Plaque in the African American-Diabetes Heart Study Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article

10 Regional migratory osteoporosis and transient osteoporosis of the hip: are they all the same Clinical Rheumatology, April 9, 2013 Review Article

11 Parathyroid hormone changes following denosumab treatment in postmenopausal osteoporosis Clinical Endocrinology, March 6, 2013

12 The effects of diabetes mellitus and diabetic nephropathy on bone and mineral metabolism in T2DM patients Diabetes Research and Clinical Practice, April 5, 2013 Review Article

13 The omega-6 arachidonic fatty acid, but not the omega-3 fatty acids, inhibits osteoblastogenesis and induces adipogenesis of human mesenchymal stem cells: potential implication in osteoporosis Osteoporosis International, April 22, 2013 Review Article

14 Where Are We 10 Years After the Womens Health Initiative? Journal of Clinical Endocrinology and Metabolism, April 19, 2013

15 Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures Journal of Bone and Mineral Research, April 5, 2013

16 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text

17 Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis Annals of Rheumatic Diseases, April 9, 2013

18 Effects of total bilirubin on the prevalence of osteoporosis in postmenopausal women without potential liver disease Journal of Bone and Mineral Metabolism, April 12, 2013 Review Article

19 Vitamin D and the cardiovascular system Osteoporosis International, March 14, 2013

20 Eldecalcitol: newly developed active vitamin D3 analog for the treatment of osteoporosis Expert Opinion on Pharmacotherapy, April 8, 2013

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology - Bone Metabolism News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology