MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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181 Control of CYP11B2/CYP11B1 Expression Ratio and Consequences for the Zonation of the Adrenal Cortex Hormone and Metabolic Research, December 17, 2012
182 Misleading Diagnosis of Renal Artery Stenosis by Magnetic Resonance Angiography in a Patient with Primary Aldosteronism Acta Chirurgica Belgica, December 17, 2012
183 Lack of sensitivity of the 1-μg low-dose ACTH stimulation test in a paediatric population with suboptimal cortisol responses to insulin-induced hypoglycaemia Clinical Endocrinology, December 14, 2012
184 The challenge of delivering endocrine care and successful transition to adult services in adolescents with congenital adrenal hyperplasia: experience in a single centre over 18 years Clinical Endocrinology, December 14, 2012
185 Severity of Is Associated with Cosmetic Appearance and Sexual Function in Women with Congenital Adrenal Hyperplasia: A Cross-Sectional Study The Journal of Sexual Medicine, December 14, 2012
186 Identification and Functional Characterization of a Large Deletion of the CYP11B1 Gene Causing an 11β-Hydroxylase Deficiency in a Chinese Pedigree Hormone Research in Paediatrics, December 11, 2012
187
Primary Adrenal Melanoma With Inferior Vena Caval Thrombus
Annals of Thoracic Surgery, December 10, 2012
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188 Preoperative masked renal damage in Japanese patients with primary aldosteronism: Identification of predictors for chronic kidney disease manifested after adrenalectomy International Journal of Urology, December 5, 2012
189 Current Update on Cytogenetics, Taxonomy, Diagnosis, and Management of Adrenocortical Carcinoma: What Radiologists Should Know American Journal of Roentgenology, November 28, 2012
190 Partial adrenalectomy minimizes the need for long-term hormone replacement in pediatric patients with pheochromocytoma and von Hippel-Lindau syndrome Journal of Pediatric Surgery, November 28, 2012
191 Distinguishing Deficiencies in the Steroidogenic Acute Regulatory Protein and the Cholesterol Side Chain Cleavage Enzyme Causing Neonatal Adrenal Failure The Journal of Pediatrics, November 27, 2012
192 Comparison of One-Tier and Two-Tier Newborn Screening Metrics for Congenital Adrenal Hyperplasia Pediatrics, November 20, 2012
193 Congenital Adrenal Hyperplasia Due to 21 Hydroxylase Deficiency: From Birth to Adulthood Seminars in Reproductive Medicine, November 13, 2012 Clinical Article
194 Long-term Follow-up of the “Wait and See” Approach to Localized Perinatal Adrenal Neuroblastoma World Journal of Surgery, November 13, 2012
195 Prenatal treatment of congenital adrenal hyperplasia: risks outweigh benefits American Journal of Obstetrics and Gynecology, November 9, 2012 Clinical Article
196 Investigation on the indication of ipsilateral adrenalectomy in radical nephrectomy: a meta-analysis Full Text Chinese Medical Journal, November 8, 2012 Evidence Based Medicine
197 Management of CAH during pregnancy: optimizing outcomes Current Opinion in Endocrinology, Diabetes and Obesity, November 7, 2012
198 The Effect of Severe Androgen Deficiency on Physical Function in Male Patients With Cancer Journal of Pain and Symptom Management, November 2, 2012
199 Nonalcoholic fatty liver disease in subjects with adrenal incidentaloma European Journal of Clinical Investigation, November 1, 2012
200 Once-daily treatment with beclomethasone dipropionate nasal aerosol does not affect hypothalamic-pituitary-adrenal axis function Annals of Allergy, Asthma, and Immunology, October 30, 2012
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Diagnostic performance of salivary cortisol in the diagnosis of Cushing's syndrome, adrenal incidentaloma and adrenal insufficiency European Journal of Endocrinology, April 24, 2013 Review Article
2 Evaluation of patients with adrenal incidentalomas Current Opinion in Endocrinology, Diabetes and Obesity, April 25, 2013 Review Article
3 Subcutaneous Hydrocortisone Administration for Emergency Use in Adrenal Insufficiency European Journal of Endocrinology, May 16, 2013 Review Article
4 Nonclassic congenital adrenal hyperplasia and the heterozygote carrier Expert Review of Endocrinology & Metabolism, May 8, 2013 Review Article
5 Men and women, so different, so similar: observations from cross-sex hormone treatment of transsexual subjects Andrologia, May 21, 2013
6 Recent advances in adrenocortical carcinoma in adults Current Opinion in Endocrinology, Diabetes and Obesity, May 2, 2013 Review Article
7 Retroperitoneal Versus Transperitoneal Laparoscopic Adrenalectomy in Adrenal Tumor: A Meta-Analysis Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, April 23, 2013 Evidence Based Medicine Review Article
8 Visceral Fat Accumulation and Postdexamethasone Serum Cortisol Levels in Patients With Adrenal Incidentaloma Journal of Clinical Endocrinology and Metabolism, May 1, 2013
9 Cystic lesions of the adrenal gland: our experience over the last 20 years Human Pathology, May 8, 2013
10 Mitotane levels predict the outcome of patients with adrenocortical carcinoma treated adjuvantly following radical resection European Journal of Endocrinology, May 28, 2013 Review Article
11 A glucocorticoid education group meeting: an effective strategy for improving self-management to prevent adrenal crisis European Journal of Endocrinology, May 3, 2013 Review Article
12 [123I]Iodometomidate Imaging in Adrenocortical Carcinoma Journal of Clinical Endocrinology and Metabolism, May 10, 2013
13 Adrenal venous sampling: promises and pitfalls Current Opinion in Endocrinology, Diabetes and Obesity, April 25, 2013 Review Article
14 Voice problems due to virilization in adult women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency Clinical Endocrinology, April 22, 2013 Review Article
15 Plasma free versus deconjugated metanephrines for diagnosis of phaeochromocytoma Clinical Endocrinology, March 6, 2013 Review Article
16 Familial SDHA Mutation Associated With Pituitary Adenoma and Pheochromocytoma/Paraganglioma Journal of Clinical Endocrinology and Metabolism, May 1, 2013
17 Factors influencing outcomes in laparoscopic adrenal surgery Langenbeck's Archives of Surgery, May 8, 2013 Review Article
18 Surgery for adrenocortical carcinoma in the Netherlands: analysis of national cancer registry data European Journal of Endocrinology, May 6, 2013
19 Pheochromocytoma revealed by acute heart failure. When should we operate? Presented at the ESES Congress, Gothenburg May 25-26, 2012 Langenbeck's Archives of Surgery, May 22, 2013
20 The prevalence and predictors of androgen deficiency in Taiwanese men with type 2 diabetes Urology, May 30, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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