MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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121 Hospitalized prenatal and childhood infections and obesity in Danish male conscripts Annals of Epidemiology , May 21, 2013 Clinical Article
122 Incidental Scintigraphic Finding of Ovarian Teratoma Containing Normal Thyroid Tissue on Post-Radioactive Iodine Therapy for Papillary Thyroid Cancer Clinical Nuclear Medicine , May 21, 2013
123 Oxidized eicosapentaenoic acids more potently reduce LXRalpha-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1beta and GPA than its intact form Full Text Lipids in Health and Disease, May 21, 2013
124 Omega-3 fatty acid therapy reduces triglycerides and interleukin-6 in hypertriglyeridemic HIV patients HIV Medicine, May 21, 2013 Clinical Article
125 Symptomatic intracranial hypertension and prolonged hypocalcemia following treatment of Paget’s disease of the skull with zoledronic acid Journal of Bone and Mineral Metabolism, May 21, 2013 Clinical Article
126 Influence of education, marital status, occupation, and the place of living on skeletal status, fracture prevalence, and the course and effectiveness of osteoporotic therapy in women in the RAC-OST-POL Study Journal of Bone and Mineral Metabolism, May 21, 2013 Review Article
127 Dynamic change and influence of osteoporotic back pain with vertebral fracture on related activities and social participation: evaluating reliability and validity of a newly developed outcome measure Journal of Bone and Mineral Metabolism, May 21, 2013 Clinical Article
128 A randomized trial comparing monthly ibandronate and weekly alendronate for osteoporosis in patients with primary biliary cirrhosis Hepatology, May 21, 2013 Clinical Article
129 Influence of Dual-Task Constraints on Whole-Body Organization During Walking in Children Who Are Overweight and Obese American Journal of Physical Medicine & Rehabilitation, May 21, 2013 Clinical Article
130 ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose Diabetes Research and Clinical Practice, May 21, 2013 Review Article
131 Short-term treatment with cabergoline can lead to tumor shrinkage in patients with nonfunctioning pituitary adenomas Pituitary, May 21, 2013 Review Article
132 Men and women, so different, so similar: observations from cross-sex hormone treatment of transsexual subjects Andrologia, May 21, 2013
133 Resection of At-Risk Mesenteric Lymph Nodes Is Associated with Improved Survival in Patients with Small Bowel Neuroendocrine Tumors World Journal of Surgery, May 21, 2013 Review Article
134 Gastric Neuroendocrine Carcinoma Staged and Followed With 18F-FDG PET/CT-A Report of 3 Cases Clinical Nuclear Medicine , May 21, 2013
135 Anti-Inflammatory Strategies for Plaque Stabilization after Acute Coronary Syndromes Current Atherosclerosis Reports, May 21, 2013 Clinical Article
136 LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men Atherosclerosis, May 21, 2013 Clinical Article
137 Individual variability in compensatory eating following acute exercise in overweight and obese women British Journal of Sports Medicine, May 21, 2013 Evidence Based Medicine
138 Injury initiates unfavourable weight gain and obesity markers in youth British Journal of Sports Medicine, May 21, 2013
139 Mosaic Isochromosome 15q and Maternal Uniparental Isodisomy for Chromosome 15 in a Patient With Morbid Obesity and Variant PWS-Like Phenotype American Journal of Medical Genetics Part A, May 21, 2013 Review Article
140 Alexander Shifrin, M.D., FACS, FACE, Endocrine Surgeon at Jersey Shore University Medical Center, presents groundbreaking case at The American Association of Endocrine Surgeons 34th Annual Meeting Meridian Health, May 21, 2013
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Over-the-Counter-Drug-Induced Thyroid Disorders Endocrine Practice, March 26, 2013 Free full text
2 Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study Journal of Clinical Endocrinology and Metabolism, March 29, 2013
3 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013
4 Treatment of Diabetic Ketoacidosis (DKA) with 2 Different Regimens Regarding Fluid Substitution and Insulin Dosage (0.025 vs. 0.1 units/kg/h) Experimental and Clinical Endocrinology & Diabetes, February 13, 2012
5 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013
6 Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes, April 24, 2013 Review Article
7 Relationships Between Serum Adiponectin and Bone Density, Adiposity and Calcified Atherosclerotic Plaque in the African American-Diabetes Heart Study Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article
8 Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies Diabetes Research and Clinical Practice, April 23, 2013 Evidence Based Medicine
9 A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review Diabetes, Obesity and Metabolism, April 4, 2013 Evidence Based Medicine Review Article
10 Significance of estimating the glomerular filtration rate for the management of hypertension in type 2 diabetes with microalbuminuria Hypertension Research, April 8, 2013
11 Validation of a Novel Method for Determining the Renal Threshold for Glucose Excretion in Untreated and Canagliflozin-treated Subjects With Type 2 Diabetes Mellitus Journal of Clinical Endocrinology and Metabolism, April 15, 2013
12 Guidelines for the use of bone metabolic markers in the diagnosis and treatment of osteoporosis (2012 edition) Journal of Bone and Mineral Metabolism, February 5, 2013 Clinical Guideline
13 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013
14 Mechanisms of Glucose Lowering of Dipeptidyl Peptidase-4 Inhibitor Sitagliptin When Used Alone or With Metformin in Type 2 Diabetes: A double-tracer study Diabetes Care, April 17, 2013
15 Treatment with the long-acting insulin analogues detemir or glargine during pregnancy in women with type 1 diabetes: comparison of glycaemic control and pregnancy outcome The Journal of Maternal-Fetal and Neonatal Medicine, April 3, 2013
16 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, April 19, 2013
17 Effects of patient-tailored atorvastatin therapy on ameliorating the levels of atherogenic lipids and inflammation beyond lowering low-density lipoprotein cholesterol in patients with type 2 diabetes Journal of Diabetes Investigation, April 3, 2013 Review Article
18 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013 Free full text
19 Metformin and Sulfonylureas in Relation to Cancer Risk in Type II Diabetes Patients: A Meta-analysis using primary data of published studies Metabolism, February 19, 2013 Evidence Based Medicine
20 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GETGOAL-DUO-1) Diabetes Care, April 8, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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