MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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121 ‘Small changes' to diet and physical activity behaviors for weight management Obesity Facts, May 22, 2013 Review Article
122 Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors Obesity Facts, May 22, 2013 Clinical Article
123 NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis Circulation, May 22, 2013 Clinical Article
124 Pheochromocytoma revealed by acute heart failure. When should we operate? Presented at the ESES Congress, Gothenburg May 25-26, 2012 Langenbeck's Archives of Surgery, May 22, 2013 Clinical Article
125 Phasing-in plasma metanephrines determination European Journal of Endocrinology, May 22, 2013 Review Article
126
Calcium co-ingestion augments postprandial glucose-dependent insulinotropic peptide1–42, glucagon-like peptide-1 and insulin concentrations in humans
European Journal of Nutrition, May 22, 2013
Clinical Article
Exclusive Author Commentary
127 Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction-Helsinki Sudden Death Study Annals of Medicine, May 22, 2013 Evidence Based Medicine Clinical Article
128 The effectiveness of teriparatide in the clinical practice-attenuation of the bone mineral density outcome by increasing age and bisphosphonate pretreatment Annals of Medicine, May 22, 2013 Evidence Based Medicine Clinical Article
129 Atherosclerosis and thromboembolic risk in atrial fibrillation: Focus on peripheral vascular disease Annals of Medicine, May 22, 2013 Review Article Clinical Article
130 Comparison of Effects of Serum n-3 to n-6 Polyunsaturated Fatty Acid Ratios on Coronary Atherosclerosis in Patients Treated With Pitavastatin or Pravastatin Undergoing Percutaneous Coronary Intervention The American Journal of Cardiology, May 22, 2013 Clinical Article
131
Computed tomography-derived cardiovascular risk markers, incident cardiovascular events, and all-cause mortality in nondiabetics: the Multi-Ethnic Study of Atherosclerosis
European Journal of Preventive Cardiology, May 22, 2013
Clinical Article
Exclusive Author Commentary
132 Identification of candidate genes encoding an LDL-C QTL in baboons Journal of Lipid Research, May 22, 2013 Clinical Article
133 Rare APOA5 Promoter Variants Associated With Paradoxical HDL Cholesterol Decrease in Response to Fenofibric Acid Therapy Journal of Lipid Research, May 22, 2013 Clinical Article
134 Obesity-related chronic kidney disease is associated with spleen-derived IL-10 Nephrology Dialysis Transplantation, May 22, 2013 Review Article
135 LDL cholesterol-lowering effects of grape extract used as a dietary supplement on healthy volunteers International Journal of Food Sciences and Nutrition, May 22, 2013 Clinical Article
136 Preoperative 4-week supplementation with omega-3 polyunsaturated fatty acids reduces liver volume and facilitates bariatric surgery in morbidly obese patients Obesity Surgery, May 22, 2013 Review Article
137 A practical and effective low-intensity dietary counseling intervention for use in primary care patients with dyslipidemia - a randomized controlled pilot trial Full Text BMC Family Practice, May 22, 2013 Clinical Article
138 Cigarette smoking, nicotine levels and increased risk for metabolic syndrome in women with polycystic ovary syndrome Gynecological Endocrinology, May 22, 2013 Clinical Article
139 Arrhythmias during and after zoledronic acid infusion patients with bone metastasis Medical Oncology, May 22, 2013 Review Article
140 Lipid-lowering pharmacotherapy and socioeconomic status: atherosclerosis risk in communities (ARIC) surveillance study Full Text BMC Public Health, May 22, 2013 Clinical Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Over-the-Counter-Drug-Induced Thyroid Disorders Endocrine Practice, March 26, 2013 Free full text
2 Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study Journal of Clinical Endocrinology and Metabolism, March 29, 2013
3 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013
4 Treatment of Diabetic Ketoacidosis (DKA) with 2 Different Regimens Regarding Fluid Substitution and Insulin Dosage (0.025 vs. 0.1 units/kg/h) Experimental and Clinical Endocrinology & Diabetes, February 13, 2012
5 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013
6 Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes, April 24, 2013 Review Article
7 Relationships Between Serum Adiponectin and Bone Density, Adiposity and Calcified Atherosclerotic Plaque in the African American-Diabetes Heart Study Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article
8 Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies Diabetes Research and Clinical Practice, April 23, 2013 Evidence Based Medicine
9 A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review Diabetes, Obesity and Metabolism, April 4, 2013 Evidence Based Medicine Review Article
10 Significance of estimating the glomerular filtration rate for the management of hypertension in type 2 diabetes with microalbuminuria Hypertension Research, April 8, 2013
11 Validation of a Novel Method for Determining the Renal Threshold for Glucose Excretion in Untreated and Canagliflozin-treated Subjects With Type 2 Diabetes Mellitus Journal of Clinical Endocrinology and Metabolism, April 15, 2013
12 Guidelines for the use of bone metabolic markers in the diagnosis and treatment of osteoporosis (2012 edition) Journal of Bone and Mineral Metabolism, February 5, 2013 Clinical Guideline
13 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013
14 Mechanisms of Glucose Lowering of Dipeptidyl Peptidase-4 Inhibitor Sitagliptin When Used Alone or With Metformin in Type 2 Diabetes: A double-tracer study Diabetes Care, April 17, 2013
15 Treatment with the long-acting insulin analogues detemir or glargine during pregnancy in women with type 1 diabetes: comparison of glycaemic control and pregnancy outcome The Journal of Maternal-Fetal and Neonatal Medicine, April 3, 2013
16 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, April 19, 2013
17 Effects of patient-tailored atorvastatin therapy on ameliorating the levels of atherogenic lipids and inflammation beyond lowering low-density lipoprotein cholesterol in patients with type 2 diabetes Journal of Diabetes Investigation, April 3, 2013 Review Article
18 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013 Free full text
19 Metformin and Sulfonylureas in Relation to Cancer Risk in Type II Diabetes Patients: A Meta-analysis using primary data of published studies Metabolism, February 19, 2013 Evidence Based Medicine
20 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GETGOAL-DUO-1) Diabetes Care, April 8, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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