Endocrinology News & Articles

MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.

Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Latest (61) Full Text Articles (2688) Focus on Reproduction

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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Clinical Pearls in Endocrinology

Pioglitazone can reduce the risk of conversion of impaired glucose tolerance to type 2 diabetes mellitus by 72%, but it was also associated with significant weight gain and edema
The most commonly reported adverse event associated with Janumet in the treatment of type 2 diabetes is diarrhea, followed by upper respiratory tract infection and headache
Maturity-onset diabetes of the young (MODY)3 can be treated with sulfonylureas with excellent results for decades

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Highlights in Endocrinology

Regulatory protein identified in T1DM

As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.

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Statins increase risk of DM in postmenopausal women

As reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up

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Determining the basal insulin dosage in T2DM

Anthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.

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Most Popular Endocrinology Articles

Last month's top read Top Articles of 2012

1 Diet beverages and the risk of obesity, diabetes, and cardiovascular disease: a review of the evidence Nutrition Reviews, May 7, 2013 Review Article

2 Treatment of Diabetic Ketoacidosis (DKA) with 2 Different Regimens Regarding Fluid Substitution and Insulin Dosage (0.025 vs. 0.1 units/kg/h) Experimental and Clinical Endocrinology & Diabetes, February 13, 2012

3 A 7-year follow-up retrospective, international, multicenter study of insulin pump therapy in children and adolescents with type 1 diabetes Acta Diabetologia, May 17, 2013 Review Article
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4 Randomized Trial of Continuous Subcutaneous Delivery of Exenatide by ITCA 650 Versus Twice-Daily Exenatide Injections in Metformin-Treated Type 2 Diabetes Diabetes Care, May 6, 2013

5 Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study Journal of Clinical Endocrinology and Metabolism, March 29, 2013

6 Mortality outcomes of different sulfonylurea drugs. The results of a 14-year cohort study of type 2 diabetic patients European Journal of Endocrinology, May 13, 2013

7 Over-the-Counter-Drug-Induced Thyroid Disorders Endocrine Practice, March 26, 2013 Free full text

8 Characteristics Associated With Maintenance of Mean A1C <6.5% in People With Dysglycemia in the ORIGIN Trial Diabetes Care, May 10, 2013

9 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled by Established Basal Insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-L) Diabetes Care, May 8, 2013

10 Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (getgoal-x) Diabetes Care, May 24, 2013

11 Effects of exercise training on quality of life, symptoms of depression, symptoms of anxiety and emotional well-being in type 2 diabetes mellitus: a systematic review Diabetologia - Clinical and Experimental Diabetes and Metabolism, May 13, 2013 Evidence Based Medicine Review Article

12 The Biopsy-Proven Benign Thyroid Nodule: Is Long-Term Follow-Up Necessary? Journal of the American College of Surgeons, May 14, 2013

13 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled by Established Basal Insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-l) Diabetes Care, May 1, 2013

14 Role of HDL cholesterol and estimates of HDL particle composition in future development of type 2 diabetes in the general population: The PREVEND Study Journal of Clinical Endocrinology and Metabolism, May 21, 2013

15 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013

16 Obesity and the Food Environment: Income and Ethnicity Differences Among People With Diabetes: The Diabetes Study of Northern California (DISTANCE) Diabetes Care, May 3, 2013 Review Article

17 The Osteocyte: An Endocrine Cell and More Endocrine Reviews, May 17, 2013 Review Article

18 Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes, April 24, 2013 Review Article

19 High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized, double-blind cross-over trial European Journal of Nutrition, May 29, 2013

20 Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies Diabetes Research and Clinical Practice, April 23, 2013 Evidence Based Medicine

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more

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Endocrinology News & Articles

Articles

Clinical Pearls in Endocrinology

Highlights in Endocrinology

Regulatory protein identified in T1DM

Statins increase risk of DM in postmenopausal women

Determining the basal insulin dosage in T2DM

Most Popular Endocrinology Articles

Other Topics in Endocrinology