MDLinx Endocrinology Overview: Our medical editors have ranked and organized papers in the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
Also on this page: MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, and clinical pearls from The Smartest Diabetes Expert as well as endocrinology topics in The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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221 Malnutrition and obesity: influence in mortality and readmissions in chronic obstructive pulmonary disease patients Journal of Human Nutrition and Dietetics, May 13, 2013 Review Article
222 Lean red meat consumption and lipid profiles in adolescent girls Journal of Human Nutrition and Dietetics, May 13, 2013 Review Article
223 Cytoreductive surgery combined with hyperthermic intrapleural chemotherapy to treat thymoma or thymic carcinoma with pleural dissemination Full Text OncoTargets and Therapy, May 13, 2013 Clinical Article
224 Obesity effect on a multimodal physiotherapy program for low back pain suffers: patient reported outcome Full Text Journal of Occupational Medicine and Toxicology, May 13, 2013 Review Article
225 The Use of the RESPeRATE Device to Lower Blood Pressure in Inner City Obese Adolescents and Children: A Pilot Feasibility Study High Blood Pressure & Cardiovascular Prevention, May 13, 2013 Clinical Article
226 5,000 steps a day to avoid higher health insurance costs? When money talks, people walk University of Michigan Health System, May 13, 2013
227 Characteristics Associated With Maintenance of Mean A1C <6.5% in People With Dysglycemia in the ORIGIN Trial Diabetes Care, May 10, 2013 Clinical Article
228 The influence of subclinical cardiovascular disease and related risk factors on cognition in type 2 diabetes mellitus: The DHS-Mind study Journal of Diabetes and its Complications, May 10, 2013 Clinical Article
229 Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks Diabetes, May 10, 2013
230 Influence of diabetes on health-related quality-of-life results in patients with acute coronary syndrome treated with coronary angioplasty Acta Diabetologia, May 10, 2013 Clinical Article
231 Estimating the Population Prevalence of Diagnosed and Undiagnosed Diabetes Diabetes Care, May 10, 2013 Clinical Article
232 Evaluation of the positive effects on insulin-resistance and β-cell measurements of vildagliptin in addition to metformin in type 2 diabetic patients Pharmacological Research , May 10, 2013 Clinical Article
233 Pharmacist-Physician Collaboration for Diabetes Care: The Diabetes Initiative Program Annals of Pharmacotherapy, May 10, 2013 Clinical Article
234 Increased Hepatic Insulin Clearance After Roux-en-Y Gastric Bypass Journal of Clinical Endocrinology and Metabolism, May 10, 2013 Clinical Article
235 Glucose Metabolism After Renal Transplantation Diabetes Care, May 10, 2013 Clinical Article
236 Effects of Ingestion Routes on Hormonal and Metabolic Profiles in Gastric-Bypassed Humans Journal of Clinical Endocrinology and Metabolism, May 10, 2013 Review Article
237 PTH (1–84) Replacement Therapy in Hypoparathyroidism: a Randomized Controlled Trial on Pharmacokinetic and Dynamic effects following 6 months of treatment Journal of Bone and Mineral Research, May 10, 2013 Clinical Article
238 Nodal status of central lymph nodes as a negative prognostic factor for papillary thyroid carcinoma Journal of Surgical Oncology, May 10, 2013 Review Article
239 Fat Distribution and Glucose Intolerance Among Greenland Inuit Diabetes Care, May 10, 2013 Review Article
240 Survey of Diabetes Care in Patients Presenting With Acute Coronary Syndromes in Canada Canadian Journal of Cardiology, May 10, 2013 Clinical Article
As published in Pancreas, researchers at the Bowman Gray School of Medicine have identified a protein (islet homeostasis protein [IHoP]) which appears to control blood glucose levels by regulating the balance between insulin and glucagon. IHoP is released from glucagon-producing cells in the islets. In both humans and animals, high levels of IHoP exist in the euglycemic state, while T1DM is associated with an absence of IHoP. The authors suggest that IHoP may serve as a target in the treatment of T1DM.
Read the article summaryAs reported in the Archives of Internal Medicine, researchers at the Mayo Clinic have shown an association between statin use and diabetes mellitus in postmenopausal women. The study involved 161,808 postmenopausal women (age range, 50-79 years) who were enrolled at 40 centers between 1993 and 1998 as part of the Women’s Health Initiative. Of the study cohort, data was available for 153,840 women without diabetes at baseline, 7.04% of whom used statins. There were 10,242 incident cases of diabetes in statin users (HR = 1.71) during 1,004,466 person-years of follow-up
Read the article summaryAnthropometric, laboratory, and clinical findings were evaluated in 681 patients with type 2 diabetes mellitus to determine the factors with the greatest influence on determining the basal insulin dosage for a target glucose level < 120 mg/dL. The authors reported that waist circumference, the duration of insulin treatment, lipid-lowering medications, use of insulin sensitizers, the HbA1c, fasting plasma glucose, HDL-C, and triglycerides levels, and severe NAFLD were most significant.
Read the article summary1 Over-the-Counter-Drug-Induced Thyroid Disorders Endocrine Practice, March 26, 2013 Free full text
2 Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study Journal of Clinical Endocrinology and Metabolism, March 29, 2013
3 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013
4 Treatment of Diabetic Ketoacidosis (DKA) with 2 Different Regimens Regarding Fluid Substitution and Insulin Dosage (0.025 vs. 0.1 units/kg/h) Experimental and Clinical Endocrinology & Diabetes, February 13, 2012
5 Elevated 1-Hour Postload Plasma Glucose Levels Identify Subjects With Normal Glucose Tolerance but Impaired {beta}-Cell Function, Insulin Resistance, and Worse Cardiovascular Risk Profile: The GENFIEV Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013
6 Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes, April 24, 2013 Review Article
7 Relationships Between Serum Adiponectin and Bone Density, Adiposity and Calcified Atherosclerotic Plaque in the African American-Diabetes Heart Study Journal of Clinical Endocrinology and Metabolism, April 2, 2013 Review Article
8 Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies Diabetes Research and Clinical Practice, April 23, 2013 Evidence Based Medicine
9 A comparison of insulin detemir and neutral protamine Hagedorn (isophane) insulin in the treatment of diabetes: a systematic review Diabetes, Obesity and Metabolism, April 4, 2013 Evidence Based Medicine Review Article
10 Significance of estimating the glomerular filtration rate for the management of hypertension in type 2 diabetes with microalbuminuria Hypertension Research, April 8, 2013
11 Validation of a Novel Method for Determining the Renal Threshold for Glucose Excretion in Untreated and Canagliflozin-treated Subjects With Type 2 Diabetes Mellitus Journal of Clinical Endocrinology and Metabolism, April 15, 2013
12 Guidelines for the use of bone metabolic markers in the diagnosis and treatment of osteoporosis (2012 edition) Journal of Bone and Mineral Metabolism, February 5, 2013 Clinical Guideline
13 Secular Changes in U.S. Prediabetes Prevalence Defined by Hemoglobin A1c and Fasting Plasma Glucose: National Health and Nutrition Examination Surveys, 1999-2010 Diabetes Care, April 22, 2013
14 Mechanisms of Glucose Lowering of Dipeptidyl Peptidase-4 Inhibitor Sitagliptin When Used Alone or With Metformin in Type 2 Diabetes: A double-tracer study Diabetes Care, April 17, 2013
15 Treatment with the long-acting insulin analogues detemir or glargine during pregnancy in women with type 1 diabetes: comparison of glycaemic control and pregnancy outcome The Journal of Maternal-Fetal and Neonatal Medicine, April 3, 2013
16 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, April 19, 2013
17 Effects of patient-tailored atorvastatin therapy on ameliorating the levels of atherogenic lipids and inflammation beyond lowering low-density lipoprotein cholesterol in patients with type 2 diabetes Journal of Diabetes Investigation, April 3, 2013 Review Article
18 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013 Free full text
19 Metformin and Sulfonylureas in Relation to Cancer Risk in Type II Diabetes Patients: A Meta-analysis using primary data of published studies Metabolism, February 19, 2013 Evidence Based Medicine
20 Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GETGOAL-DUO-1) Diabetes Care, April 8, 2013
Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetes more
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