The Latest Journal Articles in Endocrinology

1Subject-driven titration of biphasic insulin aspart 30 twice daily is non-inferior to investigator-driven titration in Chinese subjects with type 2 diabetes inadequately controlled with premixed human insulin: a randomised, open-label, parallel-group, multicentre trialJournal of Diabetes Investigation, April 21, 2015  Clinical Article
2Association of self-perceived body image with body mass index and type 2 diabetes—The ADDITION-PRO studyPreventive Medicine, April 21, 2015  Clinical Article
3Trends in the incidence of diabetes, its clinical sequelae, and associated costs in pregnancyDiabetes/Metabolism Research and Reviews, April 21, 2015  Clinical Article
4Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseasesAlimentary Pharmacology and Therapeutics, April 21, 2015  Clinical Article
5Predictors of short-term diabetes remission after laparoscopic Roux-en-Y gastric bypassObesity Surgery, April 21, 2015  Clinical Article
6New-onset diabetes after transplantation: results from a double-blind early corticosteroid withdrawal trialAmerican Journal of Transplantation, April 21, 2015  Clinical Article
7Impacts of cardiac rehabilitation on ventricular repolarization indexes and ventricular arrhythmias in patients affected by coronary artery disease and type 2 diabetesHeart & Lung; The Journal of Acute and Critical Care, April 21, 2015  Clinical Article
8Glucose intolerance in early postpartum in women with gestational diabetes: Who is at increased risk?Primary Care Diabetes, April 21, 2015  Review Article
9Detection of hard exudates in colour fundus images using fuzzy support vector machine-based expert systemJournal of Digital Imaging, April 21, 2015  Clinical Article
10The role of sodium-glucose co-transporter 2 inhibitors in the treatment of type 2 diabetesClinical Therapeutics, April 21, 2015  Review Article
1Obesity-related receptors have a unique structureRIKEN News, April 21, 2015
2Processed foods and soft drinks linked to harmful chemicalsThe University of Adelaide News, April 21, 2015
3Boosting beta cells in diabetesVanderbilt University Medical Center Research News, April 21, 2015
4Good bone, bad boneUniversity of California - Santa Barbara Science New, April 20, 2015
5Diabetes patients often experience lasting weight lossUniversity of Copenhagen Faculty of Health and Medical Sciences News, April 20, 2015
6Depression, diabetes linked to increased dementia riskUW Medicine, April 20, 2015
7Body clock genes could hold key to recurrent miscarriagesUniversity of Warwick Health and Medicine News, April 17, 2015
8Ozone air pollution could impact fertilityPennsylvania State University Health and Medicine News, April 17, 2015
9Support for GPs critical to manage and prevent obesityMonash University News, April 17, 2015
10Exercise key to fighting fat in the liver and gutThe University of Sydney News, April 16, 2015

Show Me:

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

Hypoglycemia in hospitalized diabetics and increased mortality

As reported in Endocrine Practice, hospitalized diabetics with secondary hypoglycemia (n=46408) are at increased risk for mortality (OR=1.24), early readmission (OR=1.20), and increased length of stay (OR=1.24) compared to hospitalized diabetics without hypoglycemic episodes.

Parenteral vitamin D improves insulin sensitivity

As reported in Swiss Medical Weekly, supplemental vitamin D3 (300,000 IU im) in patients (n=55) with T2DM of > 10 y duration resulted in a 12.8% decrease in HOMA-IR at 6 months compared to an increase of 10% in patients who received placebo.

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Clinical Pearls

Clinical Pearl from Smartest DocOverweight chuildren are tyoically no different from normal-weight children with respect to GFR and BP.

Clinical Pearl from Smartest DocAPOL1 nephropathy variants associate with lower levels of subclinical atherosclerosis and reduced risk of death in African Americans with type 2 diabetes.

Clinical Pearl from Smartest DocGirls who frequently binge eat are at high risk for developing diabetes.

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