Endocrinology News Articles

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Our Endocrinology medical editors have ranked and organized the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the latest endocrine news literature as it is published.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Hemoglobin A1c less than 6.5% on admission increases risk for in-hospital and 1-year mortality in patients with diabetes and chest pain Cardiovascular Endocrinology, September 2, 2014    Clinical Article

2 Twelve-month treatment with liraglutide ameliorates visceral adiposity index and common cardiovascular risk factors in type 2 diabetes outpatients Full Text Journal of Endocrinological Investigation, September 2, 2014    Clinical Article

3 Canagliflozin in Asian patients with type 2 diabetes on metformin alone or metformin in combination with sulphonylurea Diabetes, Obesity and Metabolism, September 2, 2014    Clinical Article

4 Hospital discharge algorithm based on admission HbA1c for the management of patients with type 2 diabetes Diabetes Care, September 2, 2014    Clinical Article

5 Clinical utility of dipeptidyl peptidase-4 inhibitors: a descriptive summary of current efficacy trials European Journal of Clinical Pharmacology, September 2, 2014    Review Article

6 New-onset diabetes mellitus and the analysis of Dipeptidyl-Peptidase-4 after liver transplantation Transplantation Proceedings, September 2, 2014    Clinical Article

7 Neuropathic pain phenotyping as a predictor of treatment response in painful diabetic neuropathy: Data from the randomized, double-blind, COMBO-DN study Pain, September 2, 2014    Clinical Article

8 Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: Stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity? Diabetes Research and Clinical Practice, September 2, 2014    Clinical Article

9 Increased fracture risk in patients with type 2 diabetes mellitus: An overview of the underlying mechanisms and the usefulness of imaging modalities and fracture risk assessment tools Maturitas, September 2, 2014    Clinical Article

10 The microvascular effects of insulin resistance and diabetes on cardiac structure, function, and perfusion: a cardiovascular magnetic resonance study European Heart Journal – Cardiovascular Imaging, September 2, 2014    Clinical Article

11 Serum high-sensitivity C-reactive protein levels are associated with high risk of development, not progression, of diabetic nephropathy among Japanese type 2 diabetic patients: A prospective cohort study Diabetes Care, September 2, 2014    Clinical Article

12 Comparison of the administration of teneligliptin every day versus every other day in Japanese patients with type 2 diabetes: A randomized non-inferior test The Journal of Clinical Pharmacology, September 2, 2014    Clinical Article

13 Correlation between optical coherence tomography-derived intraluminal parameters and fractional flow reserve measurements in intermediate grade coronary lesions: A comparison between diabetic and non-diabetic patients Clinical Research in Cardiology, September 2, 2014    Clinical Article

14 A qualitative synthesis of diabetes self-management strategies for long term medical outcomes and quality of life in the UK Full Text BMC Health Services Research, September 2, 2014    Evidence Based Medicine    Review Article

15 Should we listen to our clock to prevent type 2 diabetes mellitus? Diabetes Research and Clinical Practice, September 2, 2014    Clinical Article

16 Oxidized low density lipoprotein and total antioxidant capacity in type-2 diabetic and impaired glucose tolerance Saudi men Full Text Diabetology & Metabolic Syndrome, September 2, 2014    Clinical Article

17 A three-gene panel that distinguishes benign from malignant thyroid nodules International Journal of Cancer, September 2, 2014

18 Three-dimensional automated choroidal volume assessment on standard spectral-domain optical coherence tomography and correlation with the level of diabetic macular edema American Journal of Ophthalmology, September 2, 2014    Clinical Article

19 Metabolic surgery for the treatment of type 2 diabetes in pancreas after kidney transplant candidates Transplantation Proceedings, September 2, 2014    Clinical Article

20 Islet oxygen consumption rate dose predicts insulin independence for first clinical islet allotransplants Transplantation Proceedings, September 2, 2014    Clinical Article

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Highlights in Endocrinology

Vildegliptin superior to glimepiride when added to metformin

As reported in Metabolism, addition of vildegliptin (50 mg bid) to metformin in T2DM patients inadequately controlled on metformin alone was superior to the addition of glimepiride (2 mg tid) to metformin. Patients on the vildegliptin + metformin regimen lost more weight, had an improved lipid profile, had increased insulin sensitivity, and decreased post-prandial lipemia and insulinemia compared to patients on the glimepiride + metformin regimen.

Decreased survival in diabetic patients with pancreatic cancer

As reported in the British Journal of Cancer, patients with diabetes (n=62) are at increased risk of death from pancreatic cancer overall (HR=1.52) and within 3 years of diagnosis (HR=1.45).

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

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