We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Gender differences in the association between food insecurity and insulin resistance among U.S. adults: National Health and Nutrition Examination Survey, 2005-2010.Annals of Epidemiology , July 01, 2015  Clinical Article
2Effectiveness of a stepped care intervention for anxiety and depression in people with diabetes, asthma or COPD in primary care: A randomized controlled trialJournal of Affective Disorders, July 01, 2015  Clinical Article
3Contemporary risk estimates of three HbA1c variables for myocardial infarction in 101,799 patients following diagnosis of type 2 diabetesDiabetes Care, July 01, 2015  Clinical Article
4Type 2 diabetes in patients with major depressive disorder: a meta-analysis of prevalence estimates and predictorsDepression and Anxiety, July 01, 2015  Evidence Based Medicine  Review Article
5Predictors of all-cause and cardiovascular disease mortality in type 2 diabetes: Diabetes Heart StudyDiabetology & Metabolic Syndrome, July 01, 2015  Full Text  Clinical Article
6The association of body shape trajectories over the life course with type 2 diabetes risk in adulthood: a group-based modeling approachAnnals of Epidemiology , July 01, 2015  Clinical Article
7Independent association between HbA1c and arterial stiffness in healthy male adultsJournal of Diabetes Investigation, July 01, 2015  Clinical Article
8The relationship between microvascular complications and vitamin D deficiency in type 2 diabetes mellitusBMC Endocrine Disorders, July 01, 2015  Full Text  Clinical Article
9Association between comorbidities and dementia in diabetes mellitus patients: population-based retrospective cohort studyJournal of Diabetes and its Complications, July 01, 2015  Clinical Article
10Impact of inflammatory markers on the relationship between sleep quality and incident cardiovascular events in type 2 diabetesJournal of Diabetes and its Complications, July 01, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Genes responsible for increased activity during the summerUniversity of Leicester News, July 01, 2015
2Is marriage good or bad for the figure? Comparative study of nine European countriesUniversity of Basel News, June 30, 2015
3Sugary drinks linked to high death tolls worldwideTufts University News, June 30, 2015
4Medically complex patients with Type 2 diabetes have less heart disease, lower death rates if they see a specialist soon after diagnosis; healthier patients do well with family doctorsSt. Michael's Hospital, June 29, 2015
5An enzyme that enables the pathway to diabetesGarvan Institute of Medical Research News, June 29, 2015
6Johns Hopkins scientists restore normal function in heart muscle cells of diabetic ratsJohns Hopkins Medicine, June 26, 2015
7Nanoparticle 'wrapper' delivers chemical that stops fatty buildup in rodent arteriesJohns Hopkins Medicine, June 26, 2015
8Potential treatment target identified for rare form of diabetesWashington University School of Medicine in St. Louis News, June 26, 2015
9UAB Comprehensive Diabetes Center one of five centers selected to be part of HIRN-CTARUAB Medicine, June 26, 2015
10Diabetic blindness: UVA IDs best source of stem cells to battle vision lossUniversity of Virginia Health System News, June 26, 2015

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Vildegliptin superior to glimepiride when added to metformin

As reported in Metabolism, addition of vildegliptin (50 mg bid) to metformin in T2DM patients inadequately controlled on metformin alone was superior to the addition of glimepiride (2 mg tid) to metformin. Patients on the vildegliptin + metformin regimen lost more weight, had an improved lipid profile, had increased insulin sensitivity, and decreased post-prandial lipemia and insulinemia compared to patients on the glimepiride + metformin regimen.

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

Decreased survival in diabetic patients with pancreatic cancer

As reported in the British Journal of Cancer, patients with diabetes (n=62) are at increased risk of death from pancreatic cancer overall (HR=1.52) and within 3 years of diagnosis (HR=1.45).

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Clinical Pearls

Clinical Pearl from Smartest DocProbability of 45-day survival is lower in cirrhotic patients with relative adrenal insufficiency compared with non-cirrhotic patients, regardless of RAI status.

Clinical Pearl from Smartest DocAnthocyanin supplementation exerts beneficial metabolic effects in patients with type 2 diabetes.

Clinical Pearl from Smartest DocRedundant catecholamines are thought to contribute to atherosclerosis.

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