1Case management to reduce cardiovascular disease risk in American Indians and Alaska natives with diabetes: Results from the special diabetes program for Indians healthy heart demonstration projectAmerican Journal of Public Health  Clinical Article
2Drug utilization, safety, and effectiveness of exenatide, sitagliptin, and vildagliptin for type 2 diabetes in the real world: Data from the Italian AIFA Anti-diabetics Monitoring RegistryNutrition, Metabolism & Cardiovascular Diseases  Clinical Article
3Predictors of stroke associated with coronary artery bypass grafting in patients with diabetes mellitus and multivessel coronary artery diseaseThe American Journal of Cardiology  Clinical Article
4Pancreatic polypeptide response to a mixed meal is blunted in pancreatic head cancer associated with diabetes mellitusPancreatology  Clinical Article
5Covariation of the incidence of type 1 diabetes with country characteristics available in public databasesPLOS ONE  Clinical Article
6Glucose and the risk of hypertension in first-degree relatives of patients with type 2 diabetesHypertension Research  Clinical Article
7Circulating MicroRNAs associate with diabetic nephropathy and systemic microvascular damage and normalize after simultaneous pancreas-kidney transplantationAmerican Journal of Transplantation  Clinical Article
8Cost effectiveness of dipeptidyl peptidase-4 inhibitors for type 2 diabetesPharmacoEconomics  Evidence Based Medicine  Review Article
9Upper limb vascular calcification score as a predictor of late mortality in diabetic hemodialysis patientsJournal of Vascular Surgery  Review Article
10Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathyLipids in Health and Disease  Full Text
1Study: Obesity fuels silent heart damage--Evidence of heart muscle damage seen even among symptom-free peopleJohns Hopkins Medicine
2Endocrine Society publishes comprehensive report on hormone health statistics: Introductory chapter of Endocrine Facts and Figures report spotlights obesityEndocrine Society News
3UTMB study shows testosterone being prescribed when not medically neededUniversity of Texas Medical Branch at Galveston
4FDA drug safety communication: FDA cautions about using testosterone products for low testosterone due to aging; requires labeling change to inform of possible increased risk of heart attack and stroke with useFDA What's New: Drugs
5Dramatic increases in diabetes incidence, costly care and redundant spending: Leading medical association responds to “unmanageable” situation, pushes Congress to pass improved diabetes care legislationCDC
6New fat cells created quickly, but losing them...Yale School of Medicine News
7WHO calls for worldwide use of "smart" syringesWHO news
8A new stem cell advanceHarvard Gazette - Health News
9Joslin scientists find direct link between insulin resistance in the brain and behavioral disordersJoslin Diabetes Center News
10SLU researcher prevents type I diabetes in labSaint Louis University Health News

Show Me:

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

Low vitamin D levels increase risk of GDM

As reported in Acta Diabetologica, the OR for developing gestational diabetes mellitus was 1.48 for each 1 SD decrease in the 25OHD level. A decrease in 25OHD was also shown to be associated with increased insulin resistance in the second trimester.

Vildegliptin superior to glimepiride when added to metformin

As reported in Metabolism, addition of vildegliptin (50 mg bid) to metformin in T2DM patients inadequately controlled on metformin alone was superior to the addition of glimepiride (2 mg tid) to metformin. Patients on the vildegliptin + metformin regimen lost more weight, had an improved lipid profile, had increased insulin sensitivity, and decreased post-prandial lipemia and insulinemia compared to patients on the glimepiride + metformin regimen.

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Clinical Pearls

Clinical Pearl from Smartest DocBariatric surgery is associated with a 67% reduction in all-cause mortality in obese patients with type 2 diabetes.

Clinical Pearl from Smartest DocFluoroquinolones may be associated with hypoglycemia in older patients using sulfonylureas.

Clinical Pearl from Smartest DocDiabetes has the greatest risk of developing in obese men and women.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List