Effects of acute caloric restriction compared to caloric balance on the temporal response of the IGF-I system
Metabolism, 08/21/2012
Henning PC et al. – The findings indicate that free Insulin–like growth factor–I (IGF–I) decreases and IGFBP–1 increases during caloric restriction, but they are not altered with diets differing in carbohydrate and fat content. Changes in free IGF–I and IGFBP–1 are sensitive to caloric restriction, and their measurement may be valuable in monitoring the physiological response to refeeding in those consuming suboptimal calories.
