Inflammatory Ly-6Chi monocytes play an important role in the development of severe transplant arteriosclerosis in hyperlipidemic recipients
Atherosclerosis, 08/09/2012
Schiopu A et al. – The study identifies for the first time the involvement of inflammatory Ly–6Chi monocytes into the pathogenesis of TA, particularly in conditions of hyperlipidemia. Targeted therapies modulating the recruitment and activation of these cells could potentially delay coronary allograft vasculopathy and improve long–term survival of heart transplant recipients.
