Effects of exercise on inflammation markers in type 2 diabetic subjects
Acta Diabetologica,

Hopps E et al. – Recent research showed that combined exercise has greater anti–inflammatory effects than aerobic or resistance exercise alone causing a deepest decrease in C–reactive protein (CRP) , IL–6, IL–1 β, TNF– α, leptin, and resistin and a higher increase in anti–inflammatory cytokines such as IL–4, IL–10, and adiponectin.

  • Endothelial dysfunction and plasma markers of inflammation are significantly increased in type 2 diabetics.
  • Several proinflammatory cytokines, acute–phase proteins, and cell adhesion molecules, such as C–reactive protein (CRP), interleukines (IL), and tumor necrosis factor alpha (TNF– α), seem to play a role in the low–grade systemic inflammation observed in these subjects.
  • Lifestyle changes are necessary to prevent atherosclerosis and cardiovascular events.
  • Physical exercise is known to reduce markers of inflammation by decreasing adipocytokine production and cytokine release from skeletal muscles, endothelial cells, and immune system and also improving antioxidant status.
  • In type 2 diabetics, aerobic and resistance training have different effects on cytokine levels, and the differences in the modalities of exercise (type, duration, and intensity) and especially in the examined population could produce different results.

Please login or register to follow this author.
► Click here to access PubMed, Publisher and related articles...

Your Unread Messages in Endocrinology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Endocrinology Articles

1 Tattoo-like sensor can detect glucose levels without a painful finger prick American Chemical Society News, January 15, 2015

2 "Imaginary meal" tricks the body into losing weight Salk Institute News, January 7, 2015

3 Insulin therapy for type 2 diabetes mellitus JAMA, July 1, 2014    Evidence Based Medicine    Clinical Article

4 Womens age at first menstrual cycle linked to heart disease risk American Heart Association News, December 16, 2014

5 Effects of sulfonylurea as initial treatment on testosterone of middle-aged men with type 2 diabetes: a 16-week, pilot study Journal of Diabetes Investigation, December 24, 2014    Clinical Article
Exclusive Author Commentary

6 Do statins impair cognition? a systematic review and meta-analysis of randomized controlled trials Journal of General Internal Medicine, January 15, 2015    Evidence Based Medicine    Review Article

7 Controlling obesity with potato extract McGill University News, December 10, 2014

8 Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus and moderate or severe renal impairment: Observations from the SAVOR-TIMI 53 trial Diabetes Care, January 5, 2015    Clinical Article

9 Temozolomide and pasireotide treatment for aggressive pituitary adenoma: Expertise at a tertiary care center Journal of Neuro-Oncology, January 16, 2015    Clinical Article

10 Relationship of glycated hemoglobin A1c, coronary artery calcification and insulin resistance in males without diabetes Archives of Medical Research, December 3, 2014    Clinical Article

11 Metformin for primary colorectal cancer prevention in patients with diabetes: A case-control study in a US population Cancer, December 2, 2014    Clinical Article

12 Effects of testosterone treatment on glucose metabolism and symptoms in men with type 2 diabetes and the metabolic syndrome: a systematic review and meta-analysis of randomized controlled clinical trials Clinical Endocrinology, December 30, 2014    Evidence Based Medicine    Review Article    Clinical Article

13 Hypoglycemia and risk of cardiovascular disease and all-cause mortality in insulin-treated people with type 1 and type 2 diabetes: a cohort study Diabetes Care, December 19, 2014    Clinical Article

14 Effect comparison of metformin with insulin treatment for gestational diabetes: A meta-analysis based on RCTs Archives of Gynecology and Obstetrics, January 21, 2015    Clinical Article

15 Comparing dosing of basal insulin analogues detemir and glargine: Is it really unit-per-unit and dose-per-dose? Annals of Pharmacotherapy, March 12, 2014    Clinical Article

16 A high-protein breakfast induces greater insulin and glucose-dependent insulinotropic peptide responses to a subsequent lunch meal in individuals with type 2 diabetes The Journal of Nutrition, January 6, 2015    Clinical Article

17 Lobeglitazone and pioglitazone as add-ons to metformin for patients with type 2 diabetes: a 24-week, multi-centre, randomized, double-blind, parallel-group, active-controlled, phase III clinical trial with a 28-week extension Diabetes, Obesity and Metabolism, January 12, 2015    Clinical Article

18 Body mass index and stroke risk among patients with type 2 diabetes mellitus Stroke, January 9, 2015    Clinical Article

19 Glycated hemoglobin as a marker of subclinical atherosclerosis and cardiac remodeling among non-diabetic adults from the general population Diabetes Research and Clinical Practice, June 27, 2014    Clinical Article

20 Ultrasound-guided thyroid nodule biopsy: outcomes and correlation with imaging features Clinical Imaging, November 24, 2014    Clinical Article

Indexed Journals in Endocrinology: Endocrinology, Journal of Endocrinology, Clinical Endocrinology, Diabetesmore

Looking for a physician job? Let us help!

Register now for our free job placement service.
A career consultant will contact you soon.
Click Here for more information.

Get Started Now!

Free-of-charge, no obligation.

Terms and Conditions For M3 Career Consult

By registering with the M3 Career Consult service you authorize M3 USA Corporation to represent you in your job search. The following is a summary of the terms of our service and our mutual obligations to help you find a job:

  • You designate M3 to act as your agent and represent you in your job search;
  • You will not pay us for this service
  • You will advise us of any companies or positions to which you apply or have applied;
  • You will advise us if you believe you are not capable of performing a position for which we submit you, or for which you interview;
  • You will keep all information we provide you about companies or positions strictly confidential;
  • You will promptly provide us with information we request of you;
  • You will make yourself reasonably available for phone, video and in-person conversations and interviews;
  • You will be truthful in all of your communications with us; and
  • You will advise us if anything above changes.
 

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List