Tacrolimus Induced Diabetic Ketoacidosis in Nephrotic Syndrome

The Indian Journal of Pediatrics, 06/12/2012

Tacrolimus, a reversible calcineurin inhibitor, is known for its diabetogenic potential. The incidence of diabetes is less frequent among the patients of nephrotic syndrome in comparison to organ transplant recipients. Diabetic ketoacidosis (DKA) is even rarer. DKA as the first presentation of new onset tacrolimus induced transient type 1 diabetes despite a lower dose range and low trough level of the drug is being reported in a 12–y–old girl with steroid resistant nephrotic syndrome.

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