Treatments for diabetic neuropathy

Journal of the Peripheral Nervous System, 05/08/2012

Bril V – In contrast, a recent evidence–based guideline shows that effective treatments for painful Diabetic sensorimotor polyneuropathy (DSP) include: pregabalin, amitriptyline, duloxetine, venlafaxine, gabapentin, opioids, nitrate sprays, capsaicin, and transcutaneous electrical nerve stimulation. The choice of treatment is guided by the clinical status of the individual patient.

  • Diabetic neuropathy comprises disorders of peripheral nerve in diabetes patients after exclusion of other disorders and can be focal or diffuse.
  • The focal diabetic neuropathies tend to resolve spontaneously and are treated by reassurance, physiotherapy and analgesia for painful symptoms.
  • DSP is the most frequent form of diabetic neuropathy and effective disease-modifying treatment is not available beyond the interventions of optimal glycemic control, and possibly lifestyle and risk factor modification.

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