Endocrine response and perceived stress test during an experimental challenge task in adult survivors of a childhood cancer

Pediatric Blood & Cancer, 05/04/2012

It is suggested that the exposure to a life–threatening experience in childhood/adolescence increases the endocrine response to stress, and that the presence of depressive symptoms is associated with an elevation of plasma cortisol levels. A better knowledge of these mechanisms is important given that the dysregulations of the stress responses may cause psychological vulnerability.

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