Which obese youth are at increased risk for type 2 diabetes- Latent class analysis and comparison with diabetic youth

Pediatric Diabetes, 04/26/2012

Currently recommended screening of obese youth by fasting plasma glucose (FPG) is normal in 91.5%, but lacks further information to detect increased risk for youth–onset type 2 diabetes (T2D). Evaluation of obese youth by LCA identified one third (class 3) in whom the combination of higher levels of BMIz, homeostasis model assessment of insulin resistance (HOMA–IR), and family history suggests the greatest risk for T2D and targets them for further evaluation and intensive preventative management.

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