The risk of gestational diabetes mellitus among Mexican women with a history of infertility and polycystic ovary syndrome
Fertility and Sterility, 04/20/2012ReyesMunoz E et al. –
Pregnant Mexican women with a history of infertility and polycystic ovary syndrome (PCOS) are at increased risk for developing gestational diabetes mellitus (GDM). This risk should be considered beginning early in the second trimester for a timely intervention and to improve the maternal–fetal prognosis.
Group 1 (n = 52), women with a history of infertility and PCOS, and group 2 (n = 52), women without PCOS.
Inclusion criteria were singleton pregnancy with ≤13 weeks of gestation.
Exclusion criteria were pregestational diabetes mellitus and/or concomitant diseases.
Diagnosis of GDM was based on a 3–hour, 100–g oral glucose tolerance test (GTT) performed during the second trimester.
The incidence of GDM was 26.9% and 9.6% for groups 1 and 2, respectively (RR = 2.8; 95% confidence interval 1.08–7.2).
No other between–group differences were observed in the incidence of miscarriage, preterm birth, premature rupture of membranes, preeclampsia, stillbirth, fetal malformations, or small or large for gestational age newborns.
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