Loss-of-Function Mutations in MC4R Are Very Rare in the Greek Severely Obese Adult Population
Obesity, 04/13/2012Rouskas K et al.
The data suggest that Melanocortin–4 receptor (MC4R) loss–of–function mutations are rare in the Greek population. MC4R genetic deficiency is unlikely to explain the high propensity to develop severe obesity in this specific population.
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